The value of carbon nanoparticles in total thyroidectomy combined with central lymph node dissection

Abstract

Objective To explore the value of carbon nanoparticles in patients with papillary thyroid carcinoma(PTC)undergoing total thyroidectomy combined with ipsilateral central lymph node dissection. Methods 43 patients with unilateral PTC were retrospectively analyzed. All patients underwent total thyroidectomy combined with central lymph node dissection. Patients were divided into carbon nanoparticles group and the control group according to whether carbon nanoparticles were used in the operation. The operation time, postoperative hospitalization time, the serum calcium level and its rate of change, the parathyroid hormone and its rate of change on the 1st day after surgery, the number of central lymph node and the transfer rate, and the postoperative complications were compared between the 2 groups. Results There was no statistical difference between the 2 groups in operation time(P>0.05), while the postoperative hospitalization time of the carbon nanoparticles group was shorter than that of the control group(P 0.05). The incidence of postoperative complications in the carbon nanoparticles group was lower than that of the control group(P<0.05). Conclusion The application of carbon nanoparticles in total thyroidectomy combined with central lymph node dissection can contribute to the recognition and protection of parathyroid glands and its blood supply, improve the rate of central lymph node dissection, and reduce the incidence of postoperative complications. Key words: Carbon nanoparticles; Papillary thyroid carcinoma; Total thyroidectomy; Central lymph node dissection; Parathyroid glands