Abstract

The history of cancer medical treatments goes up to 1908 with the use of arsenic in this disease. An intermediate milestone was the discovery, in 1943, of an amazing tumor response using nitrogen mustard in a patient with a radio-resistant lymphoma. Chemotherapy really born with this achievement, and a plethora of antitumor agent’s came to age after 1948 till nowadays. Here, some examples of recent disease-oriented drug development approaches are presented and analyzed, as well as present limitations and challenges raised by each one

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