Abstract

This paper describes fundamental investigation to apply penetration of micro jet to disintegrate microcapsules in Drug Delivery System (DDS). Deformation processes of a bubble near curved elastic wall by shock wave observed by optical shadowgraph method using a high-speed camera. It is found that a bubble generates micro jet toward a wall and opposite side whose characteristics are affected by wall elasticity, wall curvature and a position of an initial bubble. Maximum velocity reaches 77 m/s, which corresponds to 28 MPa as water pressure. Changing wall elasticity, wall curvature and an initial bubble position can control penetration force by micro jet.

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