Abstract
Breast cancer: Metronomic therapy focused on muscarinic acetylcholine receptors
Highlights
Muscarinic acetylcholine receptors belong to the G protein coupled receptor group (GPCRs) and together with nicotinic receptors formed the cholinergic receptor family [1]
For the first time the presence of different subtypes of Muscarinic acetylcholine receptors (mAChRs) in murine and human breast tumors
The five subtypes of mAChRs are expressed in three different mammary tumors (LM2, LM3 and LMM3) that spontaneously aroused in BALB/c mice, but they are absent in normal murine mammary epithelial cells (NMuMG) [4,5,6]
Summary
Muscarinic acetylcholine receptors (mAChRs) belong to the G protein coupled receptor group (GPCRs) and together with nicotinic receptors formed the cholinergic receptor family [1]. For the first time the presence of different subtypes of mAChRs in murine and human breast tumors. The pattern of expression of mAChRs in human mammary breast tumors differs depending on the cell line analyzed.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
