Bolstering Biosecurity Amid the Biotechnology Revolution

Bioethics-CSR Divide

Previous article FreeNotes on ContributorsCorrections to this articleErrataPDFPDF PLUSFull Text Add to favoritesDownload CitationTrack CitationsPermissionsReprints Share onFacebookTwitterLinked InRedditEmailQR Code SectionsMoreTina Adcock received her Ph.D. from the Scott Polar Research Institute at the University of Cambridge and is now a postdoctoral fellow at the Rutgers Center for Historical Analysis. She specializes in the history of science, exploration, and travel in the modern North American Arctic.Gerardo Aldana is Professor of Anthropology and [email protected] at the University of California, Santa Barbara. His interests broadly consider the sciences of ancient Mesoamerica but focus on the astronomy recorded in Mayan hieroglyphic texts. He is working on the historical contextualization of scientific discovery within the Dresden Codex Venus Table.Gerardo Aldana is Professor of Anthropology and [email protected] at UCSB. His interests broadly consider the sciences of ancient Mesoamerica, but focus on the astronomy recorded in Mayan hieroglyphic texts. He is currently working on the historical contextualization of scientific discovery within the Dresden Codex Venus Table.Brian Balmer is Professor of Science Policy Studies in the Department of Science and Technology Studies, University College London. His research interests combine historical and sociological approaches and include the history of chemical and biological warfare, the history of the “brain drain,” and the role of volunteers in biomedical research.Trevor Barnes is Professor of Geography at the University of British Columbia. His research interests are in the history of twentieth-century geographical thought.Richard H. Beyler teaches history of science, intellectual history, and German history at Portland State University in Oregon. His research focuses on the political history of scientific institutions in twentieth-century Germany and on the history of biophysics before the rise of molecular biology.Karin Bijsterveld, a historian, is a professor in the Department of Technology and Society Studies at Maastricht University. She is the coeditor (with Trevor Pinch) of The Oxford Handbook of Sound Studies (Oxford, 2012) and the author of Mechanical Sound: Technology, Culture, and Public Problems of Noise in the Twentieth Century (MIT, 2008).Francesca Bordogna is Associate Professor in the Program of Liberal Studies at the University of Notre Dame, where she is also a fellow of the Reilly Center for the History and Philosophy of Science. She is the author of William James at the Boundaries (Chicago, 2008) and is now working on a book on pragmatism in early twentieth-century Italy.Anastasios Brenner is Professor of Philosophy at the Université Paul Valéry—Montpellier 3. His research focuses on the history of philosophy of science, mainly on the French tradition, as well as the current relevance of historical epistemology. His most recent book is Raison scientifique et valeurs humaines (Presses Universitaires de France, 2011).Sonja Brentjes is a researcher at the Max Planck Institute for the History of Science in Berlin, Germany. Her areas of research are the history of science, cartography, and institutions and cross-cultural exchange of knowledge in Islamicate societies and the Mediterranean world (8th–17th centuries).John Hedley Brooke is Professor Emeritus of Science and Religion at Oxford University. He has published extensively on history of chemistry, Victorian science, and the historical relations between science and religion. His latest book, edited with Ronald Numbers, is Science and Religion around the World (Oxford, 2011).Mark B. Brown is a professor in the Department of Government at California State University, Sacramento. He is the author of Science in Democracy: Expertise, Institutions, and Representation (MIT Press, 2009), as well as various publications on the politics of expertise, citizen participation, bioethics, climate change, and related topics.Stephen T. Casper ([email protected]) is Assistant Professor in Humanities and Social Sciences at Clarkson University. His research focuses on the history of neurology, neuroscience, and physiology, topics on which he has published two books as well as several articles, essays, and reviews.Pratik Chakrabarti, Reader in History at the University of Kent, has published widely on history of science, medicine, and imperialism. His works include Materials and Medicine: Trade, Conquest, and Therapeutics in the Eighteenth Century and Bacteriology in British India: Laboratory Medicine and the Tropics. He is an editor of Social History of Medicine.Cristina Chimisso (http://www.open.ac.uk/Arts/philosophy/chimisso.shtml) is Senior Lecturer in European Studies and Philosophy at the Open University, United Kingdom. She is the author of Writing the History of the Mind: Philosophy and Science in France, 1900 to 1960s (Ashgate, 2008), and Gaston Bachelard: Critic of Science and the Imagination (Routledge, 2001).Deborah R. Coen is an associate professor of history at Barnard College, Columbia University, and the author, most recently, of The Earthquake Observers: Disaster Science from Lisbon to Richter (University of Chicago Press, 2013).Claudine Cohen, a philosopher and historian of earth and life sciences, holds professorships in science at the EPHE (Life and Earth Science Section) and in the humanities at the EHESS (Center for Language and Arts) in Paris. Her publications include Science, libertinage et clandestinité à l'aube des Lumières: Le transformisme de Telliamed (Presses Universitaires de France, 2011), La méthode de Zadig: La trace, le fossile, la preuve (Seuil, 2011), The Fate of the Mammoth: Fossils, Myths, and History (Chicago, 2002), and the first translation of Leibniz's Protogaea (with André Wakefield [Chicago, 2008]). In 2012 she was awarded the Eugen Wegmann Prize of the French Geological Society for her work in the history of geosciences.Roger Cooter is Honorary Professor in the Department of History at University College London. His latest book, Writing History in the Age of Biomedicine (Yale, 2013), was written with Claudia Stein. With her he is now working on a study of capitalism, biopolitics, and hygiene in Germany and Britain from the late nineteenth century.Andrew Ede is a historian of science specializing in history of chemistry. He is the Director of the Science, Technology, and Society Program and also teaches in the Department of History and Classics at the University of Alberta in Edmonton.Michael Egan (McMaster University) is the author of Barry Commoner and the Science of Survival: The Remaking of American Environmentalism (MIT Press, 2007). He is especially interested in the toxic century and is now at work on a global history of mercury pollution since World War II.Roger Emerson is Emeritus Professor of History at the University of Western Ontario, where he taught from 1964 to 1999. He is known for studies of the Scottish Enlightenment. His latest book, published in 2013, is a biography of an amateur scientist, improver, and politician: Archibald Campbell, third Duke of Argyll (1682–1761).Sterling Evans holds the Louise Welsh Chair in Southern Plains and Borderlands History at the University of Oklahoma. His research interests include environmental history, agricultural history, and borderlands history of North America and Latin America. He is the author of The Green Republic (1999) and Bound in Twine (2007).Paul Lawrence Farber is Oregon State University Distinguished Professor Emeritus. He does research on the history of natural history, racism, and evolution. His most recent book is Mixing Races: From Scientific Racism to Modern Evolutionary Ideas (2011).Steve Fuller holds the Auguste Comte Chair in Social Epistemology at the University of Warwick. He has authored more than twenty books, with two appearing in 2014: The Proactionary Imperative: A Foundation for Transhumanism (with Veronika Lipinska) and Knowledge: The Philosophical Quest in History.Alan Gabbey is Professor Emeritus of Philosophy, Barnard College, Columbia University. He is completing a book on Spinoza (Oxford University Press) and working on a book on mechanical philosophy in the early modern period.Cathy Gere is Associate Professor of History of Science at the University of California, San Diego. She is now working on a book about utilitarianism and the sciences of pain and pleasure.Pamela Gossin, Professor of History of Science and Literary Studies and the Director of Medical and Scientific Humanities at the University of Texas at Dallas, is writing two essays on nineteenth-century British literature and astronomy and creating a digital archive of the correspondence and scientific and literary essays of John G. Neihardt.Jean-Baptiste Gouyon is a science and technology scholar with a deep interest in the history of science in its public contexts. His research focuses on film, television, and museums as popular scientific media. He holds a Ph.D. in sociology from the University of York.Rich Hamerla is Associate Dean of the Honors College and Professor of the History of Science at the University of Oklahoma. In addition to his work in the history of chemistry, he teaches classes on Weapons of Mass Destruction and science and the Cold War and has publications addressing biological weapons.Darin Hayton is Associate Professor of the History of Science at Haverford College.John Henry is Professor of the History of Science at the University of Edinburgh. He recently published a collection of earlier research, Religion, Magic, and the Origins of Science in Early Modern England (Ashgate, 2012), and an introductory textbook, A Short History of Scientific Thought (Palgrave Macmillan, 2012).Noah Heringman is Professor of English at the University of Missouri. His publications include Romantic Rocks, Aesthetic Geology (2004) and Sciences of Antiquity: Romantic Antiquarianism, Natural History, and Knowledge Work (2013).Hunter Heyck is Associate Professor of the History of Science at the University of Oklahoma, where—much to his surprise—he has recently become department chair. His second book, The Age of System: The Rise and Fracture of High Modern Social Science, has just been accepted for publication by Johns Hopkins University Press.Jan P. Hogendijk is a professor of the history of mathematics in the Department of Mathematics at the University of Utrecht. His research interests are the history of the mathematical sciences in ancient Greek and medieval Islamic civilizations and the history of mathematics in the Netherlands between 1600 and 1850.Thierry Hoquet is Professor of Philosophy of Science in the Philosophy Faculty, University of Lyon 3, and a Junior Member of the Institut Universitaire de France. He specializes in the history of the life sciences, from Buffon to Darwin. He is currently completing a study on the way sex is variously defined by biologists.David A. Hounshell is Roderick Professor of Technology and Social Change at Carnegie Mellon University. He is the author of From the American System to Mass Production, 1800–1932 (1984), and “Planning and Executing ‘Automation’ at Ford Motor Company, 1945–1965: The Cleveland Engine Plant and Its Consequences,” in Fordism Transformed: The Development of Production Methods in the Automobile Industry, edited by Haruhito Shiomi and Kazuo Wada (Oxford, 1995).James Hull is an associate professor of history at the University of British Columbia (Kelowna) and an affiliate of the Institute for the History and Philosophy of Science and Technology (Toronto). He is Editor of Scientia Canadensis, the journal of the Canadian Science and Technology Historical Association.Georgia Irby is Associate Professor of Classical Studies at the College of William and Mary. Her research interests include the history of Greek and Roman science and the representation of science, broadly defined, in nonscientific Greco-Roman literature.Douglas M. Jesseph is Professor of Philosophy at the University of South Florida. He is the author of Berkeley's Philosophy of Mathematics, Squaring the Circle: The War between Hobbes and Wallis, and numerous articles on mathematics, methodology, and philosophy in the early modern period.Andrew Jewett is Associate Professor of History and of Social Studies at Harvard University and the author of Science, Democracy, and the American University: From the Civil War to the Cold War (Cambridge, 2012). He is currently a fellow at the National Humanities Center.Ann Johnson is an Associate Professor of History at the University of South Carolina. She works on the history of the physical sciences, engineering, technology, and modern Europe. Her most recent book was: Hitting the Brakes: Engineering Design and the Production of Knowledge (Duke, 2009)Paul Josephson teaches history at Colby College in Waterville, Maine, and is the author of the forthcoming Building a Soviet Arctic.Horst Kant studied physics, history, and philosophy of science. Since 1995 he has been a research scholar at the Max Planck Institute for the History of Science. His main subjects are history of physics in the nineteenth and twentieth centuries (especially institutional, social, and biographical aspects) and history of atomic physics.Peter P. Kirschenmann is Professor Emeritus in the Philosophy of the Natural Sciences and Philosophical Ethics at Vrije Universiteit, Amsterdam. He has worked on a great variety of philosophical topics; a selection of his published articles can be found in his Science, Nature, and Ethics: Critical Philosophical Studies (Delft: Eburon, 2001).W. R. Laird is Associate Professor of History at Carleton University, Ottawa, where he teaches medieval history and the history of science. He is the author of The Unfinished Mechanics of Giuseppe Moletti (Toronto, 2000) and coeditor (with Sophie Roux) of Mechanics and Natural Philosophy before the Scientific Revolution (Dordrecht, 2008).Christoph Lüthy directs the Center for the History of Philosophy and Science at Radboud University, Nijmegen. He is particularly interested in the history of natural philosophy and of scientific iconography. In 2012 he published David Gorlaeus (1591–1612): An Enigmatic Figure in the History of Philosophy and Science (Amsterdam University Press).Robert MacDougall is Associate Professor of History at the University of Western Ontario and the author of The People's Network: The Political Economy of the Telephone in the Gilded Age.Lisa Messeri is a postdoctoral fellow at the University of Pennsylvania. She holds a Ph.D. from MIT's Program in History, Anthropology, and Science, Technology, and Society. She is completing a manuscript entitled Placing Outer Space: An Earthly Ethnography of Other Worlds.Robert G. Morrison is Associate Professor of Religion at Bowdoin College. He is the author of Islam and Science: The Intellectual Career of Ni˙zām al-Dīn al-Nīsābūrī (Routledge, 2007).Stephanie Moser is Professor of Archaeology at the University of Southampton. She has published widely on the visual representation of archaeology and the portrayal and reception of the ancient world.Adriana Novoa is a cultural historian whose specialty is science in Latin America. She and Alex Levine have coauthored two books about Darwinism in Argentina (From Man to Monkey and Darwinistas!). Her articles have been published in the Journal of Latin American Studies in Context, the Latinoamericanist, Revista Hispánica Moderna, and elsewhere.Benjamin B. Olshin is Associate Professor of Philosophy, History of Science and Technology, and Design at the University of the Arts in Philadelphia. His research areas include the history of cartography and exploration, ancient science and engineering, the philosophy of contemporary physics, and traditional modes of knowledge transmission.John Parascandola taught at the University of Wisconsin–Madison before serving as Chief of the History of Medicine Division of the National Library of Medicine and as Public Health Service Historian. He is the author of The Development of American Pharmacology: John J. Abel and the Shaping of a Discipline.Valentina Pugliano is a Wellcome Trust Research Fellow in the Department of History and Philosophy of Science at the University of Cambridge and a Junior Research Fellow at Christ's College, Cambridge. Her work focuses on early modern artisanal practices and the interaction between medicine and science in the Republic of Venice and the Ottoman Levant.Nicky Reeves is a postdoctoral researcher at the Department of History and Philosophy of Science, University of Cambridge, where he is a member of the Arts and Humanities Research Council–funded project “The Board of Longitude, 1714–1828: Science, Innovation, and Empire in the Georgian World,” conducted in association with the National Maritime Museum, Greenwich.Raul Rojas is a professor of computer science in Berlin. He is the founder of the Konrad Zuse Internet Archive, the largest online source of documents and blueprints written or drafted by Konrad Zuse. He is the author of Die Rechenmaschinen von Konrad Zuse (Springer-Verlag, 1998).Nicolaas Rupke is Johnson Professor in the College at Washington and Lee University, having recently retired from the Chair of the History of Science at Göttingen. Among his books are Richard Owen: Biology without Darwin (Chicago, 2009) and Alexander von Humboldt: A Metabiography (Chicago, 2008). He is now working on the non-Darwinian tradition in evolutionary biology.Dr Juanita Feros Ruys is the Director of the University of Sydney Node of the ARC Centre of Excellence for the History of Emotions and is currently investigating Scholastic approaches to demonology. Her study of the late poetic works of Peter Abelard will be published by Palgrave in 2014.Tilman Sauer teaches history of science at the University of Bern and is a Senior Editor with the Einstein Papers Project at the California Institute of Technology, Pasadena.John Scarborough is Professor in the School of Pharmacy and the Departments of History and Classics (quondam) at the University of Wisconsin–Madison. His books include Roman Medicine (1969; 1976) and Pharmacy and Drug Lore in Antiquity: Greece, Rome, Byzantium (2010). He is coeditor (with Paul T. Keyser) of the Oxford Handbook of Science and Medicine in the Classical World (forthcoming).Andrew Scull is Distinguished Professor of Sociology and Science Studies at the University of California, San Diego. His recent books include Madness: A Very Short Introduction, Hysteria: The Disturbing History, and Durkheim and the Law (2nd ed.), with Steven Lukes.J.B. Shank is a graduate of Stanford University with a Ph.D. in European History and Humanities. He is currently completing a book entitled Before Voltaire: Newton, “Newtonianism,” and the Beginning of the French Enlightenment which is under contract with the University of Chicago Press.Ruth Lewin Sime is Emeritus Professor of Chemistry at Sacramento City College. She is the author of Lise Meitner: A Life in Physics and is now writing a biographical study of Otto Hahn.Daniel Lord Smail is a professor of history at Harvard University, where he works on deep human history and the history and anthropology of Mediterranean societies between 1100 and 1600. His current research approaches transformations in the material culture of later medieval Mediterranean Europe using household inventories and inventories of debt recovery from Lucca and Marseille.Vassiliki Betty Smocovitis is Professor of History of Science at the University of Florida. She is the author of Unifying Biology: The Evolutionary Synthesis and Evolutionary Biology. Her interests include the history of twentieth-century evolutionary biology, genetics, and systematics, and she has published extensively in the history of the botanical sciences in North America.Rudolf Werner Soukup, of the Technische Universität Vienna, works on alchemy and early chemistry, chemical research in the Habsburg Monarchy, and Robert Bunsen's library in Althofen. He is the author of Alchemistisches Gold, Paracelsistische Pharmaka (1997), Die wissenschaftliche Welt von gestern (2004), Chemie in Österreich (2007), and Pioniere der Sexualhormonforschung (2010).David Spanagel is an assistant professor of history at Worcester Polytechnic Institute. His first book (Johns Hopkins University Press, forthcoming) is a study of the political, material, and cultural contexts of geological ideas in New York State during the early nineteenth century, centering on Amos Eaton.Max Stadler is Chair for Science Studies at ETH Zurich. Professor Stadler works on the history of perception, the nervous system, technology and design. He has published extensively on the history of neuroscience.Larry Stewart is Professor of History and Director of the “Situating Science” node at the University of Saskatchewan. He is the author of The Rise of Public Science (1992) and, with Margaret Jacob, Practical Matter (2004), as well as various essays on the dissemination of scientific knowledge since Newton. He is now writing a study of experiment during the Enlightenment and the first industrial revolution and is editing, with Erica Dyck, a collection of essays on the use of humans in experiments.Heiko Stoff is Guest Professor for the History of Science and Technology at the Technical University of Braunschweig. He is the author of Ewige Jugend: Konzepte der Verjüngung vom späten 19. Jahrhundert bis ins Dritte Reich (Böhlau, 2004) and Wirkstoffe: Eine Wissenschaftsgeschichte der Hormone, Vitamine und Enzyme, 1920–1970 (Stuttgart, 2012).Bruno J. Strasser is a professor at the University of Geneva and an adjunct professor at Yale University. He is the author of a book on the history of molecular biology in postwar Europe, La fabrique d'une nouvelle science: La biologie moléculaire à l'age aomique, 1945–1964 (Florence, 2006). He is now finishing a book on the history of biomedical collections and databases.Laurence Totelin is a Wellcome Trust Research Fellow in the Department of History and Philosophy of Science at the University of Cambridge. Her publications include Hippocratic Recipes: Oral and Written Transmission of Pharmacological Recipes in Fifth- and Fourth-Century Greece (Brill, 2009).Janet Vertesi is Assistant Professor of Sociology at Princeton University. Her recent research examines NASA's robotic space exploration missions; her book, Seeing Like a in on the is forthcoming from the University of Chicago in is a Fellow at the University of Her publications include the book University Press, and several research on the to the of Her current project with the history of is a professor in the Department of History at the University of California, San Diego. His research is on the cultural history of early modern science, the and of His most recent book is The and is Professor of History and Philosophy at State College in New is Professor of Philosophy at the University of York and a of early modern and the reception of She is the author of at the Origins of (Oxford, and The World Previous article by of the History of Science Society by The History of Science Society. articles this

This dissertation examines some of the economic issues surrounding patenting by smaller life science firms. In this context patents are viewed as firm assets that have a value separate from the patented innovation itself, derived from rents that accrue to the monopoly rights granted by the patent. Patents also have costs associated with their acquisition, including legal and patent office fees as well as the time and effort required to move them through the process from application to granted status. The first essay investigates one facet of the cost of patent acquisition, pendency time. Patents which take longer to be granted can place a higher cost on the applicant firm, in the form of foregone revenues, as well as on society, as longer pendency slows the rate of innovation and creates uncertainty for other innovators. Much research in this area concentrates on the influence of patent characteristics on pendency. This essay uses a more comprehensive model that also includes the experience and interests of three stakeholders in the patenting process: applicants, their attorneys, and patent examiners. I find that applicant behavior is a significant factor in longer pendency. This suggests that pendency offers benefits to the applicant, including the aforementioned uncertainty on the part of potential competitors and more time to assess the nature and value of the invention and tailor the patent to market conditions. The second essay turns to the subject of patent value, and examines the relationship between academic science and industrial innovation. Knowledge from academic science can be an important input for innovation in the life sciences. Previous research has described the impact of science intensity, defined as the number of scientific references in the patent, on patent value Scientific knowledge is not homogeneous, though, any more than are the patents that make use of it. Variations in quality may have a separate influence. Here I develop a novel measure of the quality of the scientific references in granted patents, augmenting previous research mainly concerned with the quantity of scientific references. I find that higher quality science is significantly related to patents of greater technological importance and thus overall value. The third essay is concerned with how the value of patents changes over the course of a technology life cycle. Previous studies of value and pendency have reached conflicting conclusions based on whether technology position was included. This essay uses patents related to polymerase chain reaction technology to trace changes in value and the pace of change, as well as other patent characteristics, over a technology cycle. I find that patent value and the pace of technological change both change non-linearly over the cycle. The results suggest that these two factors may interact such that during periods of rapid technological change shorter pendency is in the applicant's interest, while longer pendency may be preferred during periods of slower change.

Technology is the main cause of emerging careers in life science. As technological change occurs at unprecedented speeds, it becomes increasingly important to develop mechanisms that can foster skills highly demanded in emerging careers. Technical and Vocational Education and Training (TVET) is an integral part of the education system with mechanisms that can prepare such skills. Some of emerging careers in life science includes Biotechnology and Bioinformatics. This paper examines some of compelling issues and challenges for consideration in TVET training when aligning skills for emerging careers in life science. The paper also identifies priorities of improvement in science education and strategies for interventions that will link life science to job creation and career skills. The compelling issues and strategies includes; making quality education in science a priority in secondary schools and to recognize its impact far into the future for emerging careers in life science, training with strong link with the industries and innovative delivery of instruction which can actively engage students in learning and developing skills. Other considerations include a carefully sequenced and flexible curriculum which must meet increasing and ever-changing knowledge and skills demands. Also hands-on activities in laboratories should remain an indispensable constituent of effective learning and acquiring skills. Awareness rising for aspirants in emerging careers is also very important which includes encouraging more women in those emerging careers in life science. Emerging careers in life science are expected to substantially create an impact on scientific, social welfare and economic development of

This paper focuses on issues concerning the introductory college mathematics sequence with an emphasis on students interested in the life sciences, and concentration on the time after the publication of BIO2010 (BIO2010 in Transforming Undergraduate Education for Future Research Biologists, National Academies of Science, Medicine and Engineering, Washington, 2003). It also explores the potential uses of books targeted at introductory mathematics courses for life science majors today. As relevant background, we look at the evolution of the way that calculus has been taught over the past 50 years, including at the high school level. We also explore the implications of changes in technology and course delivery, such as online education. As we discuss different books and introductory course ideas, we focus on the needs of biology students, the inclusion of real-world problems and models, the role of technology, and the impact of data science. The paper is organized as follows: Sect. 1 provides some personal background with calculus dating back to the 1970s, and changes in calculus prior to BIO2010. Section 2 introduces goals for an introductory mathematics sequence and evaluates the calculus sequence in light of those goals. Sections 3–7 discuss various issues that will help to understand issues and challenges for introductory mathematics for the life sciences: Calculus in high school (Sect. 3), equity issues relative to calculus and other math topics (Sect. 4), the impact of online education (Sect. 5), math as a stumbling block for college students (Sect. 6), and the increasing importance and value of teaching data science (Sect. 7). Section 8 reviews the development of books in light of these issues and challenges. The last section (Sect. 9) summarizes conclusions.

The best-selling Differentiating Instruction With Menus series has helped teachers nationwide differentiate instruction for their high-ability learners with easy-to-use menus and exciting tools to challenge and reach gifted and advanced students in the classroom. Each book includes an updated, student-friendly rubric that can assess different types of products, free choice proposal forms to encourage independent study, and new and favorite challenging menus to meet the needs of these diverse higher level learners. Readers will also be able to save time by using updated guidelines that reflect changes in technology for each of the products included in the menus and find direct alignment with standards approved in recent years. Topics addressed in Differentiating Instruction With Menus: Science (Grades 6-8, 2nd ed.) include process skills, physical sciences, life sciences, and Earth and space sciences.Grades 6-8

Quite a few attempts have been made to define the “New Economy”. One indirect approach is to stress the two input factors which increasingly shape developed economies: knowledge-based services and information and communication technology (ICT). Another line is to stress the interrelated changes in technology, organisation and consumption that came up in the last decade of the twentieth century. Paul Geroski offers a third definition which is very nice and easy: he defines the New Economy by the existence of two sectors; for him, “New Economy” is information and communication technology (ICT) plus life sciences. Countries with large shares of these two industries in production and consumption are frontrunners in the New Economy.

Methods for data analysis in the biomedical, life, and social (BLS) sciences are developing at a rapid pace. At the same time, there is increasing concern that education in quantitative methods is failing to adequately prepare students for contemporary research. These trends have led to calls for educational reform to undergraduate and graduate quantitative research method curricula. We argue that such reform should be based on data-driven insights into within- and cross-disciplinary use of analytic methods. Our survey of peer-reviewed literature analyzed approximately 1.3 million openly available research articles to monitor the cross-disciplinary mentions of analytic methods in the past decade. We applied data-driven text mining analyses to the "Methods" and "Results" sections of a large subset of this corpus to identify trends in analytic method mentions shared across disciplines, as well as those unique to each discipline. We found that the t test, analysis of variance (ANOVA), linear regression, chi-squared test, and other classical statistical methods have been and remain the most mentioned analytic methods in biomedical, life science, and social science research articles. However, mentions of these methods have declined as a percentage of the published literature between 2009 and 2020. On the other hand, multivariate statistical and machine learning approaches, such as artificial neural networks (ANNs), have seen a significant increase in the total share of scientific publications. We also found unique groupings of analytic methods associated with each BLS science discipline, such as the use of structural equation modeling (SEM) in psychology, survival models in oncology, and manifold learning in ecology. We discuss the implications of these findings for education in statistics and research methods, as well as within- and cross-disciplinary collaboration.

Methods for data analysis in the biomedical, life, and social (BLS) sciences are developing at a rapid pace. At the same time, there is increasing concern that education in quantitative methods is failing to adequately prepare students for contemporary research. These trends have led to calls for educational reform to undergraduate and graduate quantitative research method curricula. We argue that such reform should be based on data-driven insights into within- and cross-disciplinary use of analytic methods. Our survey of peer-reviewed literature analyzed approximately 1.3 million openly available research articles to monitor the cross-disciplinary mentions of analytic methods in the past decade. We applied data-driven text mining analyses to the “Methods” and “Results” sections of a large subset of this corpus to identify trends in analytic method mentions shared across disciplines, as well as those unique to each discipline. We found that the t test, analysis of variance (ANOVA), linear regression, chi-squared test, and other classical statistical methods have been and remain the most mentioned analytic methods in biomedical, life science, and social science research articles. However, mentions of these methods have declined as a percentage of the published literature between 2009 and 2020. On the other hand, multivariate statistical and machine learning approaches, such as artificial neural networks (ANNs), have seen a significant increase in the total share of scientific publications. We also found unique groupings of analytic methods associated with each BLS science discipline, such as the use of structural equation modeling (SEM) in psychology, survival models in oncology, and manifold learning in ecology. We discuss the implications of these findings for education in statistics and research methods, as well as within- and cross-disciplinary collaboration.

and the genetic engineering of plants such as tobacco to produce

In core foundation of the most important priority area of Ukraine “Life sciences, new technologies of prevention and common diseases treatment” are the current problems of modern Ukrainian society, labor productivity in all economy sectors. Rational distribution of funds and a high level of implementation of scientific (scientific and technical) outputs are the driving force of progressive technological structural changes in the economy and an important factor in ensuring the competitiveness of the national economy. The article presents the results of the author’s research on the state of implementation of one of the six priority areas defined by the Law of Ukraine “About Priority Areas of Science and Technology Development” for the period up to 2020, and 12 priority thematic areas of research, scientific and technical developments specified priority and approved by the Resolution of the Cabinet of Ministers of Ukraine from 07.09.2011 No. 942 for the period up to 2020 (as amended in accordance with the resolution of the Cabinet of Ministers of Ukraine from 23.08.2016 No. 556, which supplemented priority thematic areas list with new areas aimed at ensuring national security, increasing the state’s defense capabilities, protecting the civilian population, medicine, the agricultural sector, as well as clarifying the wording of a number of priority thematic areas).

Współcześnie przemysł life science (w tym biotechnologiczny i farmaceutyczny – B&F) uznawany jest za jeden z najważniejszych i najszybciej rozwijających się sektorów gospodarki zaawansowanych technologii. Przemysł ten jest ważnym czynnikiem rozwoju społeczno-gospodarczego poszczególnych krajów oraz regionów i w znaczący sposób wpływa na kształtowanie się gospodarki opartej na wiedzy. Szczególną rolę w kreowaniu rozwoju gospodarczego odgrywają wielkie korporacje międzynarodowe, posiadające bogate zaplecze naukowe i kapitał. Korporacje działające w tym sektorze gospodarki zmuszone są do podejmowania ciągłych działań innowacyjnych, co związane jest z szybkimi zmianami technologicznymi, a tym samym z dużym ryzykiem inwestycyjnym. Przedmiotem przeprowadzonych badań są transnarodowe korporacje biotechnologiczne i farmaceutyczne wyróżnione spośród 2000 największych korporacji różnych sektorów gospodarczych magazynu „Forbes”. Celem badań jest określenie prawidłowości przemian, jakie zachodziły w układach przestrzennych oraz w potencjale ekonomicznym transnarodowych korporacji biotechnologicznych i farmaceutycznych. Współcześnie można zaobserwować wzrost znaczenia tych podmiotów wśród największych korporacji światowych. Szczególnie szybko rozwija się przemysł biotechnologiczny (w tym biotechnologia biała), co jest spowodowane m.in. starzeniem się społeczeństwa, chorobami cywilizacyjnymi, wzrostem gospodarczym w krajach rozwijających się oraz zauważalną akceleracją rozwoju nowych technologii. Jako główne rejony rozwoju biotechnologii i farmacji podaje się kraje wysoko rozwinięte (np. USA, kraje Europy Zachodniej, Japonię). Jednak w ostatnich latach można zauważyć nasilający się proces delokalizacji przemysłu (w tym głównie w aspekcie produkcji i badań klinicznych). Proces delokalizacji sektora life science powiązany jest również z powstawaniem nowych rynków zbytu (np. Azja, Ameryka Południowa) i poszukiwaniem przez korporacje regionów proinwestycyjnych (np. Chiny, Indie). Jednakże spośród wszystkich czynników najważniejsza dla rozwoju biotechnologii sektorów life science jest infrastruktura B&R, wysokiej jakości kapitał ludzki i czynniki infrastrukturalne (w tym odpowiednie normy etyczne i prawne).

At a time when welfare contracts are in crisis, it is timely to discuss different forms of disruptive innovation and responses of medical finance and economic systems, especially adjusting with new instruments for recovery and innovative solutions for health reforms. The objective of this paper is to propose some ways to develop a framework for policy changes affecting life science sectors and healthcare. It aims to analyze the types of relationships between health or medical systems and the economic systems. Medical systems used to be generally closed systems, but the new forms of delivery, especially with increase of telehealth and Mobile health (Mhealth) solutions (boosted by the COVID-19 pandemic, such as online consultations), have open traditional boundaries and generate more interactions with economic systems. It also led to new institutional arrangements at federal, national, or local levels, with different power games according to the history of institutions and cultural differences between countries. Which system dynamics prevail will also depend on the political systems in place, for instance very innovative open innovation systems dominated by private players such as the USA empower individuals and favor intuitive and entrepreneurial states. On the other hand, systems historically dominated by socialized insurance or former communist countries, have investigated "attunements" or adaptation mechanisms in system intelligence. However, systemic changes are not only implemented by traditional rulers (government agencies, federal reserve banks) but also face the emergence of systemic platforms dominated by Big Tech players. The new agendas expressed for instance in the United Nation (UN) framework and the set of Sustainable Development Goals (SDGs) for climate change and sustainable growth, also require global adjustment of supply and demand, in a context where the traditional drug/vaccine split is challenged by the new technologies (e.g., mRNA technologies). Investment for drug research led to the development of COVID-19 vaccines, but also potential cancer vaccines. Finally, welfare economics is increasingly criticized among economist circles; it requires new design for global value assessment framework, facing growing inequalities and inter-generational challenges in aging populations. This paper contributes to new models of developments and different frameworks for multiple stakeholders with major technological changes.

THE NEW GEOGRAPHY OF JOBS. By Enrico Moretti. 294pp.; maps, bibliog., index. Boston, New York: Houghton Mifflin Harcourt, 2012. $28 (doth), ISBN 9780574750118. Just when pundits are declaring the increasing unimportance of geography because of technology, another book comes along such as The New Geography of Jobs, which demonstrates the exact opposite--that location matters now more than ever. Enrico Moretti has demonstrated in this easy-to-read book that centers of innovation in the United States are becoming increasingly important for jobs and wages for those working in the innovation sectors, as well as those in noninnovation sectors. The new and changing geography of jobs also contributes to widening regional disparities in health, education, and political involvement. With technological change, the fortunes of regions and cities rise and fall though not as one would predict. As Moretti demonstrates, in the late 1960s, few were predicting that Menlo Park, in what is now called Silicon Valley, would become the economic engine that it has become and that other nearby communities, which seemed to have more economic prospects would see their fortunes decline considerably. He terms this widening economic gap between communities the Great Divergence. While racial segregation in the United States is lessening, communities are becoming more segregated by income and educational levels. This long-term trend has been overlooked with the focus on short-term economic indicators that drive much of the political agenda. While the focus of the book is on the new geography of jobs, it also points out the there is a growing gap between people with different educational levels. But people with less education also have lower mobility rates and are thus less able to migrate to a more prosperous community. Innovation jobs will never comprise the majority of employment in any community, and are roughly 10 percent nationally, but they are important because of the enormous impact they have on other sectors of the local economy in the form of a multiplier effect. Innovation jobs are difficult to define as they take different forms--but they have in common that they employ human capital and ingenuity. It encompasses advanced manufacturing, information technology, life sciences, medical devices, robotics, new materials, and nanotechnology--basically all jobs that generate new ideas and new products. Jobs in the innovation sector are replacing those in manufacturing, which for a long time were the backbone of the U.S. economy. Based on careful analysis of data and interviews, Moretti weaves the results into the narrative as examples of how growth in the innovation sector has affected particular communities. The example he gives of the location of Microsoft is one such interesting story. While Microsoft and Seattle are now synonymous, it wasn't inevitable that the company would be located there. …

Research in the life sciences is a large, diverse enterprise conducted by hundreds of thousands of individuals, who are supported by thousands of organizations, including academic departments; research institutes; museums; state and federal government agencies; state, regional, and local associations; and a host of consortia and coalitions. Among those organizations, scientific societies have played an integral role in advancing biological research for centuries. However, the twenty-first century has ushered in a series of economic, social, and technological changes, the impacts of which are changing the fundamental nature of how these societies fulfill their roles and are threatening the continued existence of some of those organizations (Travis 2010). Conversations in the community of biological scientists—especially in the executive councils of scientific societies—have suggested to the American Institute of Biological Sciences (AIBS) that individual societies are facing acute challenges and that these might be widespread. Indeed, AIBS itself is experiencing challenges that echo those being discussed by its member organizations. Declines in AIBS’s individual membership counts, along with the changing economics of the scientific enterprise and especially that of academic publishing, have raised significant questions about the sustainability of many of our