Abstract
Ultrafiltration of blood finds application in the conventional dialysis and adsorber-ultrafilter artificial-kidney systems. The ultrafilters used for these processes are either flat-membrane thin-channel flow systems or bundles of capillary-like hollow fibres. The design analysis of hollow-fibre and thin-channel ultrafilters is carried out by assuming 2-dimensional and axisymmetric flow of a Newtonian fluid accompanied by convective and diffusive mass transfer across the semipermeable membrane wall. The wall permeation velocity is assumed to be small and (a) decaying exponentially along the flow direction and (b) proportional to the transmembrane pressure difference. The ultrafilter is simulated for the operation of (a) a conventional dialyser and (b) and ultrafilter as used in the adsorber-ultrafilter artificial kidney. The parametric analysis of the ultrafilter is studied.
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