Abstract
Objective To observe the occurrence of hyperglycemia, hypoglycemia, and high blood sugar fluctuation inpatients with type 2 diabetes mellitus who have chronic obstructive pulmonary disease (COPD) and are treated with moderate glucocorticoid, and to explore reasonable blood sugar monitoring and hypoglycemic schemes avoiding the harm of hyperglycemia, hypoglycemia and high blood sugar fluctuation to the patients. Methods 73 patients who had type 2 diabetes mellitus and chronic obstructive pulmonary disease (COPD) and were enrolled in our hospital from June, 2018 to June, 2019 were selected. The 33 patients treated at our hospital from June to November, 2018 were selected as a control group; and the 40 patients from January to June, 2019 were selected as an experimental group. The respiratory doctors and nurses treated the patients in the control group with a blood glucose monitoring program and a hypoglycemic program. The medical staff in the experimental group were trained by the full-time medical staff of Endocrinology Department for one month; and the blood glucose monitoring program and the hypoglycemic program were implemented according to the endocrinology specifications. Results There were no statistical differences in fasting and pre-meal blood glucose, glycated hemoglobin, total cholesterol, triglyceride, high density lipoprotein, low density lipoprotein, and body mass index between the two groups during hospitalization (all P>0.05). The blood glucose 2 h adter meal was (11.91±4.86) mmol/L in the experimental group, and was (13.64±5.43) mmol/L in the control group, with a statistical difference (P<0.05). The experimental group had occurred 21 times hyperglycemia, 3 times hypoglycemia, and one HI, and the control group 139, 23, and 43 times, with statistical differneces (all P<0.05). Conclusions Improvement of blood sugar monitoring and hypoglycemic regimen in patients treated with glucocorticoid can make their blood glucose stable, significantly reduce the the incidences of hyperglycemia, hypoglycemia and HI as well as the risk factors in the process of glucocorticoid application and complications, avoid all kinds of accidents, and improve their quality. Key words: Type 2 diabetes mellitus; Chronic obstructive pulmonary disease; Glucocorticoid; Blood glucose monitoring; Hypoglycemia
Published Version
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