Abstract
Bloch analysis of spin response to arbitrary pulse sequences is shown to be a powerful design technique that is very easy to implement and to apply, in particular, to the problem of solvent suppression in proton NMR. As a result of extensive experimenting with the technique, we conclude that soft pulse sequences are, in general, preferable to hard pulse sequences. Detailed comparison of soft and hard pulse sequences are made to show the practical advantages of the former. A number of NMR measurements, including T 1 and solvent saturation transfer, on samples of human hemoglobin both in water and inside intact red blood cells, are given as illustrations.
Published Version
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