Abstract
Bismuth subsalicylate preparations are over-the-counter remedies for gastrointestinal complaints. Intestinal absorption in small amounts (<1%) 1 Slikerveer A Helmich RB Van-Der-Voet GB et al. Ab-sorption of bismuth from several bismuth compounds during in vivo perfusion of rat small intestine. J Pharm Sci. 1995; 84: 512-515 Crossref PubMed Scopus (9) Google Scholar does occur and may cause neurotoxicity 2 Gordon MF Abrahms RI Rubin DB et al. Bismuth subsalicylate toxicity as a cause of prolonged encephalopathy with myoclonus. Mov Disord. 1995; 10: 220-222 Crossref PubMed Scopus (69) Google Scholar and skin reactions. 3 Goodman LS Gilman A. The pharmacological basis of therapeutics. in: MacMillan, New York1955: 1114-1119 Google Scholar We describe a patient with black granules on the skin after ingestion of PeptoBismol® brand of bismuth subsalicylate.
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