Abstract
The biotransformations of 4-methylcyclohexanone and 4-ethylcyclohexanone were investigated using 10 kinds of anthracnose fungi as biocatalysts. 4-Methylcyclohexanone and 4-ethylcyclohexanone were reduced to the corresponding cis- and trans-alcohols respectively. In the case of 4-methylcyclohexanone, it was transformed to mainly trans-4-methylcyclohexanol by all the fungi examined. In particular, the ratio of cis- and trans-alcohol products was shown to be 1:81 with high stereoselectivity by Colletotrichum lagenarium after a 7-day incubation period. The biotransformation of 4-ethylcyclohexanone by C lagenarium, C dematium MAFF410046, C trifolii MAFF305389, C fragariae, C atramentarium MAFF712102, C lindemuthianum (C-1), C lindemuthianum (C-3) and C lindemuthianum (C-13) produced mainly trans-4-ethylcyclohexanol. On the other hand, cis-alcohol was formed with stereoselectivity by Glomerella cingulata and C graminicola MAFF305460. © 2000 Society of Chemical Industry
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Journal of Chemical Technology & Biotechnology
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
