Abstract
ABSTRACT Background/objective: This research aims to investigate the circadian rhythm in individuals with COVID-19 and healthy controls. We tested the association between disruptions of biological rhythms and psychiatric symptoms. Methods/participants: This cross-sectional study included a sample of adults with COVID-19 and controls. Biological rhythms were assessed by the Biological Rhythms in Neuropsychiatry Assessment Interview (BRIAN), while depression, sleep quality, anxiety, and stress levels were analyzed using specific scales. Results: 96 cases and 199 controls were assessed. Compared to controls, the cases showed higher biological rhythms dysfunction, especially in the sleep, activity, and eating behavior domains. Cases showed higher levels of stress, depressive symptoms, and anxiety compared to controls. BRIAN scores were positively correlated with the severity of depressive symptoms, anxiety, insomnia, and stress. Conclusion: COVID-19 is associated with circadian rhythms disturbances. Disruptions in the biological rhythm were related to a higher presence of depressive symptoms, anxiety, and stress.
Published Version
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