Abstract
ABSTRACT Objective Amniotic membrane (AM) extract is a promising tool in regenerative medicine, which offers similar therapeutic effects as intact AM but with a simpler and safer approach. AM displays several subregional variances. Method The quantitative analysis of hepatocyte growth factor (HGF) and transforming growth factor-beta 1 (TGF-β1) in placental and reflected AM sections were assayed by enzyme-linked immunosorbent assay. Results Detection of high levels of HGF and TGF-β1 with variation in concentration between the placental and reflected portions of the same membrane. Conclusion Understanding AM subregional variations would optimize AM extract preparation for specific regenerative medicine therapies.
Published Version
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