Abstract
BackgroundFlaxseed meal, the de-oiled by-product of flaxseed processing, has been extensively studied as a rich source of protein (with protein content up to 40%). Flaxseed protein (FP) and FP-derived peptides from flaxseed meal have documented physiological activity, e. g. angiotensin-converting enzyme (ACE) inhibition, antibacterial activity and anti-diabetic effect as well as antioxidant capacity. However, the mechanisms for their physiological activities and the structure & bioactivity relationships have not been summarised previously. In addition, commercial production of FP and its peptides is still not achievable due to challenges in production scale up and real-time quantification of bioactives. Scope and approachPrevious studies including isolation and structural features of FP as well as the production, biological activities and the structural & functional relationships of bioactive peptides/hydrolysates from FP are herein reviewed. This article would be helpful to promote the application of FP/bioactive peptides in both research and commercialization. Key findings and conclusionsAs interactions between flaxseed gum (FG) and FP interfere with FP isolation, removal of FG before extraction is necessary. Therefore, combination strategies are required for FP production. Lab-scale peptide generation is both costly and time-consuming. To overcome this challenge, in-silico methods are suggested, including mathematical simulation of protein hydrolysis, bioprospecting for bioactive peptides, and molecular docking studies. Gastrointestinal analysis is recommended for studying practical applications of FP-derived peptides as bioactive nutrients.
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call