Abstract
BackgroundGlycosmis is a genus of evergreen glabrous shrub and distributed all over India. It possesses various medicinal properties and is used in indigenous medicine for cough, rheumatism, anemia, and jaundice. Glycosmis arborea is a rich source of alkaloids, terpenoids, coumarins, as well as flavonoids.ResultsThe chemical investigation of methanol fraction of the leaves of G. arborea led to the isolation of one new flavone C-glycoside along with three known flavanoids, named as 5,7-dihydroxy-2-[4-hydroxy-3-(methoxy methyl) phenyl]-6-C-β-d-glucopyranosyl flavone (4), 5,7,4′-trihydroxy-3′-methoxy flavone (1), 5,4′-dihydroxy-3′-methoxy-7-O-β-d-glucupyranosyl flavanone (2), and 5,4′-dihydroxy-3′-methoxy-7-O-(α-l-rhamnosyl-(1‴→6‴)-β-d-glucopyranosyl) flavanone (3), respectively. The structures of all compounds were elucidated with the help of nuclear magnetic resonance spectrometry. Pure compounds and fractions were evaluated for pest antifeedant and antimicrobial activity.ConclusionFour compounds were isolated from the leaves of G. arborea. Among them, compound 4 showed significant antimicrobial activity.
Highlights
Glycosmis is a genus of evergreen glabrous shrub and distributed all over India
Glycosmis is a genus of evergreen glabrous shrub, distributed in warm and temperate regions of the world, and is a rich source of alkaloids and amide; terpenoids, coumarins, and flavonoids were reported [1,2]
As a part of our ongoing studies aimed at the phytochemical and pharmacological characterization of this plant, we found that hexane and methanol fractions of the ethanol extract of G. arborea leaves showed significant antifeedant and antimicrobial activity
Summary
Glycosmis is a genus of evergreen glabrous shrub and distributed all over India. It possesses various medicinal properties and is used in indigenous medicine for cough, rheumatism, anemia, and jaundice. Glycosmis arborea is a rich source of alkaloids, terpenoids, coumarins, as well as flavonoids. Glycosmis is a genus of evergreen glabrous shrub, distributed in warm and temperate regions of the world, and is a rich source of alkaloids and amide; terpenoids, coumarins, and flavonoids were reported [1,2]. As a part of our ongoing studies aimed at the phytochemical and pharmacological characterization of this plant, we found that hexane and methanol fractions of the ethanol extract of G. arborea leaves showed significant antifeedant and antimicrobial activity. We decided to carry out a detailed study to investigate the chemical composition of G. arborea.
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