Abstract
Dysgerminoma is a rare malignant neoplasm, associated with hormonal dysfunctions, which occurs in canine and feline females from middle age to elderly, without racial predisposition. In the present report, we described a case of ovarian dysgerminoma in a dog, only abdominal distension, persistent vulvar bloody discharge and apathy. The animal in question underwent exploratory laparotomy, where general neoformations were detected in the ovaries, and a lymph node with abnormal characteristics was also found. Therefore, surgery for ovariosalpingoisterectomy and puncture of a fragment of the lymph node altered for incisional biopsy was performed. The diagnosis was made through histopathological examination of the ovaries of the fragment derived from the lymph node, the result of which indicated the presence of dysgerminoma in both ovaries and in the lymph node, characterizing a metastasis. In view of this result, the chemotherapy protocol with the association of carboplatin and vinblastine was instituted, which proved to be effective and not very toxic to the animal, with no clinical sign of metastasis being identified after its use.
Highlights
According to Wellons and colleagues [1], dysgerminoma, which can be called a germinoma, is a tumor that can be located in the testicles, ovaries and extragonal zones, with the same histological basis, consisting of large, round, oval cells or polygonal with clear cytoplasm and large, round nucleus with one or two prominent nucleoli, grouped in nests separated by fibrous septa with abundant lymphocytes, called Langhans cells, with areas of necrosis and granulomatous reaction
Dysgerminoma is a rare malignant neoplasm, associated with hormonal dysfunctions, which occurs in canine and feline females from middle age to elderly, without racial predisposition
We described a case of ovarian dysgerminoma in a dog, only abdominal distension, persistent vulvar bloody discharge and apathy
Summary
According to Wellons and colleagues [1], dysgerminoma, which can be called a germinoma, is a tumor that can be located in the testicles, ovaries and extragonal zones, with the same histological basis, consisting of large, round, oval cells or polygonal with clear cytoplasm and large, round nucleus with one or two prominent nucleoli, grouped in nests separated by fibrous septa with abundant lymphocytes, called Langhans cells, with areas of necrosis and granulomatous reaction. We described a case of ovarian dysgerminoma in a dog, only abdominal distension, persistent vulvar bloody discharge and apathy.
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