Abstract

Objective
 Vitamin B12 deficiency is a common condition in
 childhood and various neurological, hematological,
 and dermatological findings could be seen due to its
 deficiency. The aim of the study is to evaluate the
 hematological findings in children diagnosed with
 vitamin B12 deficiency.
 Materials and Methods
 Hematological data of children with B12 deficiency
 who were examined in Pediatric Hematology
 Department were retrospectively reviewed.
 Results
 Hematological data of one hundred twenty-four
 patients were assessed in our study. Anemia,
 thrombocytopenia and leucopenia were detected in
 48 patients, 8 patients and 6 patients, respectively.
 Two infants presented with prolonged jaundice and
 hemolytic anemia. The mean vitamin B12 levels of the
 patients were 97.3±30.6 (5-140) pg/ml.
 Conclusion
 Vitamin B12 deficiency is a common disease in
 developing countries and it is mostly of maternal
 origin. In our study, vitamin B12 deficiency in mothers
 of 42 out of 52 infants (80%) were discovered. This
 percentage clearly shows the importance of the vitamin
 B12 level determination in pregnant women and its
 treatment in case of deficiency. Patients with vitamin
 B12 deficiency might be admitted to the hospital for
 various reasons. Therefore, it is recommended to
 keep in mind that vitamin B12 deficiency might be
 the base of various diseases, especially for patients
 presenting prolonged jaundice and hemolytic anemia.

Full Text
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