Avaliação dos principais fatores de risco para alta variabilidade glicêmica em uma Unidade de Terapia Intensiva

Abstract

Glycemic variability (GV) is an important evaluation parameter for cardiovascular complications. We aimed to identify factors associated with the risk of high glycemic variability in an Intensive Care Unit. In this prospective cohort with 168 adult patients, we first described the variables by absolute and relative frequency and then identified the risk factors for high GV by logistic regression within a 95% confidence interval. Of the 168 patients, 22.6% had high GV, 62.5% were male, 51.2% were under 40 years old, 52.4% had a clinical diagnosis, 73.8% were using mechanical ventilation, 12.3% had > 30% mortality risk (Apache II), 17.9% had sepsis, 47.6% were hypertensive, and 28.0% of the patients died. In the final analysis, patients with sepsis (OR: 2.40; 95%CI: 1.10 – 5.94), over 40 years old (OR: 3.23; 95%CI 1.34-7.81) and who evolved to death (OR: 3.15; 95%CI 1.40-7.08) were those who had a greater chance of high GV. Patients with sepsis and those over 40 years old need greater surveillance of glycemic control to reduce mortality in the ICU.