Atypical Presentation of Acute Lymphoid Leukemia as Hypercalcemia and Bilateral Renal Calculi

Madhu Bj ,Ns Chithambaram ,G Harish ,Vijaya Sarathi

doi:10.31031/gjem.2018.02.000546

Abstract

Atypical Presentation of Acute Lymphoid Leukemia as Hypercalcemia and Bilateral Renal Calculi

Highlights

Hypercalcemia presenting as acute leukemia is a rare but an important complication in childhood leukemia
Hypercalcemia usually results in nonspecific constitutional symptoms, it can manifest as a life-threatening metabolic emergency [1]
We report a child who presented with severe hypercalcemia with bilateral renal calculi who was later diagnosed to have acute leukemia

Summary

Introduction

Hypercalcemia presenting as acute leukemia is a rare but an important complication in childhood leukemia. We report a child who presented with severe hypercalcemia with bilateral renal calculi who was later diagnosed to have acute leukemia. The boy had a fracture of spine following fall from stairs for which he was treated conservatively He had history of vomiting, 3-4 episodes per day, decreased appetite and weight loss in the last 9 months. He had constipation, pain abdomen, frequent passing of urine, bone pains and generalized weakness. In view of the above findings, hematological malignancy was suspected, and bone marrow aspiration was done This showed normal erythroid maturation, myeloid series markedly suppressed, and eosinophils are mildly increased. The parents deferred any further evaluation and treatment despite counseling

Discussion

Findings

Conclusion