Atomic force microscopy of biomolecules

Abstract

Biological atomic force microscopy (also known as scanning force microscopy) has advanced in many areas. Some of the new applications of atomic force microscopy to DNA and protein research are outlined. Advances have occurred in both imaging and nonimaging uses of atomic force microscopy. Advances in atomic force microscopy imaging have been seen both in the imaging of immobile samples and in the imaging of motion and processes. Advances in nonimaging atomic force microscopy include the use of force curves to measure intermolecular forces, force mapping, and measurements of protein motion.