Association of Predicted Damaging De Novo Variants on Ventricular Function in Individuals With Congenital Heart Disease.

Abstract

HomeCirculation: Genomic and Precision MedicineAhead of PrintAssociation of Predicted Damaging De Novo Variants on Ventricular Function in Individuals With Congenital Heart Disease No AccessLetterRequest AccessAboutView PDFSections ToolsAdd to favoritesDownload citationsTrack citationsPermissions ShareShare onFacebookTwitterLinked InMendeleyReddit Jump toNo AccessLetterRequest AccessAssociation of Predicted Damaging De Novo Variants on Ventricular Function in Individuals With Congenital Heart Disease Matthew J. Lewis, MD, MPH, Alexander Hsieh, PhD, Lu Qiao, PhD, Renjie Tan, PhD, Brigitte Kazzi, MD, Alexandra Channing, MD, Emily Griffin, MS, Vaidehi Jobanputra, PhD, Jennifer Su, Chowdhury Shahryar, Lazaros Kochilas, William Gaynor, MD, Teresa Lee, MD, Elizabeth Goldmuntz, MD, Mark Russell, MD, Seema Mital, MD, Martin Tristani, MD, Martina Brueckner, MD, Jane Newburger, MD, Yufeng Shen, PhD and Wendy K. Chung, MD, PhD Matthew J. LewisMatthew J. Lewis Correspondence to: Matthew Lewis, MD, MPH, Columbia University Irving Medical Center, Herbert Irving Pavilion, 161 Fort Washington Ave, Room 627, New York, NY 10032. Email E-mail Address: [email protected] https://orcid.org/0000-0002-8991-0638 Department of Medicine, Columbia University Irving Medical Center, New York. (M.J.L., B.K., W.K.C.) Search for more papers by this author , Alexander HsiehAlexander Hsieh Departmens of Systems Biology and Biomedical Informatics, Columbia University Irving Medical Center, New York. (A.H., R.T., Y.S.) Search for more papers by this author , Lu QiaoLu Qiao https://orcid.org/0000-0002-5977-4946 Department of Pediatrics, Columbia University Irving Medical Center, New York. (L.Q., A.C., E.G., V.J., T.L., W.K.C.) Search for more papers by this author , Renjie TanRenjie Tan https://orcid.org/0000-0001-6087-4584 Departmens of Systems Biology and Biomedical Informatics, Columbia University Irving Medical Center, New York. (A.H., R.T., Y.S.) Search for more papers by this author , Brigitte KazziBrigitte Kazzi Department of Medicine, Columbia University Irving Medical Center, New York. (M.J.L., B.K., W.K.C.) Search for more papers by this author , Alexandra ChanningAlexandra Channing https://orcid.org/0000-0001-9971-8239 Department of Pediatrics, Columbia University Irving Medical Center, New York. (L.Q., A.C., E.G., V.J., T.L., W.K.C.) Search for more papers by this author , Emily GriffinEmily Griffin https://orcid.org/0000-0001-5193-2041 Department of Pediatrics, Columbia University Irving Medical Center, New York. (L.Q., A.C., E.G., V.J., T.L., W.K.C.) Search for more papers by this author , Vaidehi JobanputraVaidehi Jobanputra https://orcid.org/0000-0003-0962-7873 Department of Pediatrics, Columbia University Irving Medical Center, New York. (L.Q., A.C., E.G., V.J., T.L., W.K.C.) Search for more papers by this author , Jennifer SuJennifer Su Department of Pediatrics, Children’s Hospital Los Angles, CA (J.S.). Search for more papers by this author , Chowdhury ShahryarChowdhury Shahryar Department of Pediatrics, Medical University of South Carolina, Charleston (C.S.). Search for more papers by this author , Lazaros KochilasLazaros Kochilas https://orcid.org/0000-0002-4686-634X Department of Pediatrics, Emory University, Atlanta, GA (L.K.). Search for more papers by this author , William GaynorWilliam Gaynor Department of Pediatric Cardiac Surgery, The Children’s Hospital of Philadelphia, PA. (W.G.) Search for more papers by this author , Teresa LeeTeresa Lee Department of Pediatrics, Columbia University Irving Medical Center, New York. (L.Q., A.C., E.G., V.J., T.L., W.K.C.) Search for more papers by this author , Elizabeth GoldmuntzElizabeth Goldmuntz https://orcid.org/0000-0003-2936-4396 Department of Pediatrics, The Children’s Hospital of Philadelphia, PA.(E.G.) Search for more papers by this author , Mark RussellMark Russell https://orcid.org/0000-0003-4855-9260 Division of Pediatric Cardiology, University of Michigan, Ann Arbor (M.R.). Search for more papers by this author , Seema MitalSeema Mital https://orcid.org/0000-0002-7643-4484 Department of Pediatrics, Hospital for Sick Children, University of Toronto, Ontario, Canada (S.M.). Search for more papers by this author , Martin TristaniMartin Tristani https://orcid.org/0000-0001-5916-442X Department of Pediatrics, University of Utah, Salt Lake City (M.T.). Search for more papers by this author , Martina BruecknerMartina Brueckner Department of Pediatrics, Yale University, New Haven, CT (M.B.). Search for more papers by this author , Jane NewburgerJane Newburger https://orcid.org/0000-0002-7794-9017 Department of Cardiology, Boston Children’s Hospital, MA (J.N.). Search for more papers by this author , Yufeng ShenYufeng Shen https://orcid.org/0000-0002-1299-5979 Departmens of Systems Biology and Biomedical Informatics, Columbia University Irving Medical Center, New York. (A.H., R.T., Y.S.) Search for more papers by this author and Wendy K. ChungWendy K. Chung https://orcid.org/0000-0003-3438-5685 Department of Medicine, Columbia University Irving Medical Center, New York. (M.J.L., B.K., W.K.C.) Department of Pediatrics, Columbia University Irving Medical Center, New York. (L.Q., A.C., E.G., V.J., T.L., W.K.C.) Search for more papers by this author Originally published3 Mar 2023https://doi.org/10.1161/CIRCGEN.122.003900Circulation: Genomic and Precision Medicine. 2023;0:e003900FootnotesCorrespondence to: Matthew Lewis, MD, MPH, Columbia University Irving Medical Center, Herbert Irving Pavilion, 161 Fort Washington Ave, Room 627, New York, NY 10032. Email [email protected]columbia.edu Previous Back to top Next FiguresReferencesRelatedDetails Advertisement Article InformationMetrics © 2023 American Heart Association, Inc.https://doi.org/10.1161/CIRCGEN.122.003900PMID: 36866680 Originally publishedMarch 3, 2023 Keywordsinformed consentcongenitalventricular dysfunctionexome sequencingnucleotidePDF download Advertisement SubjectsCongenital Heart DiseaseGenetics