Gene Silencing Therapy in Hereditary (Variant) Transthyretin Cardiac Amyloidosis: A Puzzling Case of Decreasing Pyrophosphate Uptake on Scintigraphy.

Abstract

HomeCirculation: Cardiovascular ImagingAhead of PrintGene Silencing Therapy in Hereditary (Variant) Transthyretin Cardiac Amyloidosis: A Puzzling Case of Decreasing Pyrophosphate Uptake on Scintigraphy No AccessCase ReportRequest AccessAboutView PDFSections ToolsAdd to favoritesDownload citationsTrack citationsPermissions ShareShare onFacebookTwitterLinked InMendeleyReddit Jump toNo AccessCase ReportRequest AccessGene Silencing Therapy in Hereditary (Variant) Transthyretin Cardiac Amyloidosis: A Puzzling Case of Decreasing Pyrophosphate Uptake on Scintigraphy Dia A. Smiley, Andrew J. Einstein, Akiva Mintz, Mrinali Shetty, Nicholas Chan, Stephen T. Helmke, Ketan Bhatia, Kim Goldner, Thomas H. Brannagan, Denisse D. Santana and Mathew S. Maurer Dia A. SmileyDia A. Smiley Seymour, Paul, and Gloria Milstein Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York-Presbyterian Hospital. (D.A.S., A.J.E., M.S., N.C., S.T.H., D.D.S., M.S.M.) Search for more papers by this author , Andrew J. EinsteinAndrew J. Einstein https://orcid.org/0000-0003-2583-9278 Seymour, Paul, and Gloria Milstein Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York-Presbyterian Hospital. (D.A.S., A.J.E., M.S., N.C., S.T.H., D.D.S., M.S.M.) Department of Radiology, Columbia University Irving Medical Center, New York-Presbyterian Hospital. (A.J.E., A.M., K.B., K.G.) Search for more papers by this author , Akiva MintzAkiva Mintz Department of Radiology, Columbia University Irving Medical Center, New York-Presbyterian Hospital. (A.J.E., A.M., K.B., K.G.) Search for more papers by this author , Mrinali ShettyMrinali Shetty https://orcid.org/0000-0003-3263-5134 Seymour, Paul, and Gloria Milstein Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York-Presbyterian Hospital. (D.A.S., A.J.E., M.S., N.C., S.T.H., D.D.S., M.S.M.) Search for more papers by this author , Nicholas ChanNicholas Chan Seymour, Paul, and Gloria Milstein Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York-Presbyterian Hospital. (D.A.S., A.J.E., M.S., N.C., S.T.H., D.D.S., M.S.M.) Search for more papers by this author , Stephen T. HelmkeStephen T. Helmke https://orcid.org/0000-0003-2764-3009 Seymour, Paul, and Gloria Milstein Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York-Presbyterian Hospital. (D.A.S., A.J.E., M.S., N.C., S.T.H., D.D.S., M.S.M.) Search for more papers by this author , Ketan BhatiaKetan Bhatia Department of Radiology, Columbia University Irving Medical Center, New York-Presbyterian Hospital. (A.J.E., A.M., K.B., K.G.) Search for more papers by this author , Kim GoldnerKim Goldner Department of Radiology, Columbia University Irving Medical Center, New York-Presbyterian Hospital. (A.J.E., A.M., K.B., K.G.) Search for more papers by this author , Thomas H. BrannaganThomas H. Brannagan https://orcid.org/0000-0002-1812-8331 Department of Neurology, Columbia University Irving Medical Center, New York-Presbyterian Hospital. (T.H.B.) Search for more papers by this author , Denisse D. SantanaDenisse D. Santana Seymour, Paul, and Gloria Milstein Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York-Presbyterian Hospital. (D.A.S., A.J.E., M.S., N.C., S.T.H., D.D.S., M.S.M.) Search for more papers by this author and Mathew S. MaurerMathew S. Maurer Correspondence to: Mathew S. Maurer, MD, Department of Medicine, Columbia University Irving Medical Center, New York-Presbyterian Hospital, 622 W 168th St, PH12 Stem Room 134, New York, NY 10032. Email E-mail Address: [email protected] https://orcid.org/0000-0002-1867-0526 Seymour, Paul, and Gloria Milstein Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York-Presbyterian Hospital. (D.A.S., A.J.E., M.S., N.C., S.T.H., D.D.S., M.S.M.) Search for more papers by this author Originally published19 Jun 2023https://doi.org/10.1161/CIRCIMAGING.123.015243Circulation: Cardiovascular Imaging. 2023;0:e015243FootnotesFor Sources of Funding and Disclosures, see page xxx.Correspondence to: Mathew S. Maurer, MD, Department of Medicine, Columbia University Irving Medical Center, New York-Presbyterian Hospital, 622 W 168th St, PH12 Stem Room 134, New York, NY 10032. Email [email protected]columbia.edu Previous Back to top Next FiguresReferencesRelatedDetails Advertisement Article InformationMetrics © 2023 American Heart Association, Inc.https://doi.org/10.1161/CIRCIMAGING.123.015243PMID: 37334703 Originally publishedJune 19, 2023 Keywordspositron emission tomographyprealbumintransthyretinamyloidosiscardiomyopathyPDF download Advertisement SubjectsCardiomyopathyHeart FailureImagingNuclear Cardiology and PET