Abstract
Background; Stroke is a global health problem. Stroke is responsible for major disabilities in adult population, and is 2 nd leading cause of deaths all over the world. Different studies have reported dyslipidemia as major cause of stroke in different populations. Objective; To determine the frequency of dyslipidemias in patients with ischemic stroke at Nishtar Hospital Multan. Material and methods; All the cases of stroke (n=240) Patients having finding on CT scan brain (plain) consistent with ischemic stroke of either sex aged less than 80 years were enrolled in this cross-sectional study from department of Medicine, Nishtar Hospital, Multan. Complete history about onset of illness, diabetes, hypertension and cardiac illness of the patients was taken. Baseline laboratory investigations including lipid profile and Hb A 1 c were done. Results; Of these 240 study cases, 155 (64.6 %) were male patients and 85 (35.4%) were female patients. Mean age of our study cases was 68.37 ± 14.55 years (with minimum age was 34 years while maximum age was 79 years). Out of these 240 study cases, 138 (57.5 %) were from poor families, 53(22.1 %) were diabetic and only 11 out of 53 (20.75%) had controlled glycemic levels. Hypertension was present in 182 (75.8%) of our study cases and 39 (16.3 %) were obese. Smoking was present in 101 (42.1%), previous history of stroke was present in 35 (14.6%) and 83 (34.6%) were Saraikis. Mean duration of illness was 2.24 ± 0.53 months and 135 (56.3%) had disease duration more than 1 month. Mean serum cholesterol level was 202.06 ± 45.36 mg/dl, mean serum LDL level was 91.13 ± 10.24 mg/dl, mean serum triglyceride level was 147.51 ± 20.21 mg/dl and mean serum HDL level was 42.92 ± 3.85 mg/dl and dyslipidemia was present in 85 (35.4 %). Diabetes was significantly associated with dyslipidemia (p = 0.002). Conclusion; Very high frequency of dyslipidemia was noted in diabetic patients having ischemic stroke. Dyslipidemia was significantly associated with diabetes, hypertension, obesity, smoking, previous history of stroke and ethnicity. Early diagnosis followed by timely management can help reduce disease morbidity and improve clinical outcomes in these patients. Keywords; ischemic stroke, dyslipidemia, frequency. DOI : 10.7176/JMPB/62-14 Publication date: December 31 st 2019
Highlights
Introduction; Stroke (Cerebrovascular accidents) is characterized by sudden development of neurological deficit
Material and methods; All the cases of stroke (n=240) Patients having finding on CT scan brain consistent with ischemic stroke of either sex aged less than 80 years were enrolled in this cross-sectional study from department of Medicine, Nishtar Hospital, Multan
Dyslipidemia was significantly associated with diabetes, hypertension, obesity, smoking, previous history of stroke and ethnicity
Summary
Introduction; Stroke (Cerebrovascular accidents) is characterized by sudden development of neurological deficit. 5 million die and another 5 million are left incapacitated[2,3,4,5] It is a huge public health problem imposing both a large disease burden and a large economic burden on the individual families and countries. Ischemic Stroke occurs as a result of an obstruction within a blood vessel supplying blood to the brain It accounts for 60-90% percent of all stroke cases in Pakistan. In Pakistan, more than 75000 deaths occur due to stroke and a large number of patients are left with partial or total disabilities which puts socio economic burden on the family and society 15. Dyslipidemia has been a known major risk factor for coronary heart disease. The purpose of this study is to determine the frequency of dyslipidemias in the patients of ischemic stroke in the targeted population
Sign-in/Register to view highlights & summary 
Published Version (
Free)
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call