Abstract
Natural compounds derived from plants have been extensively employed in conventional treatments and are a key component of medicinal products. Perovskia abrotanoides, a plant native to Pakistan, is historically used to cure several ailments, while little is known regarding its pharmacological properties. This study aimed to investigate the pharmacological characteristics of the crude methanolic extract of Perovskia abrotanoides. Phytochemical analysis indicated many phytoconstituents capable of profound antioxidant activity, which may play an important role as anti-asthmatic and hepato-protectant. Its anti-asthmatic and hepatoprotective properties were evaluated using models of histamine-induced asthma and liver damage brought on by carbon tetrachloride, respectively. Research was also conducted on the extract's phytotoxic, antibacterial, and anticancer effects. The results demonstrated strong hepatoprotective and anti-asthmatic effects; while no harm other than a drop in platelet count was noted. Also, the extract showed significant antimicrobial activities against Staphylococcus aureus. However, no apoptotic or anticancer potential was found.
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