Abstract

Assessment of oral health-related quality of life among children with acute leukemia

Highlights

  • Leukemia can develop from lymphoid or myeloid cells and is generally classified as acute if cells are in an early stage of differentiation[1]

  • According to a study conducted in the Pediatric Hematology-Oncology Department of Abderrahim Harouchi Hospital Casablanca, Morocco between January 2006 and December 2013, of 142 cases of acute leukemia, acute lymphoblastic leukemia (ALL) represented 89.5 % of cases[2]

  • The paediatric dentist plays an important role in the diagnosis, prevention, maintenance, and treatment of oral complications which can compromise the quality of life of children affected by leukemia[4]

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Summary

Introduction

Leukemia can develop from lymphoid or myeloid cells and is generally classified as acute if cells are in an early stage of differentiation[1]. The oral cavity represents a privileged site for the development of complications related to both ALL and chemotherapy. These complications are mostly acute (mucositis, hyposialia, opportunistic infections, haemorrhage) but sometimes, long-term dental and craniofacial sequelae can develop as well. The paediatric dentist plays an important role in the diagnosis, prevention, maintenance, and treatment of oral complications which can compromise the quality of life of children affected by leukemia[4]. To estimate the oral health-related quality of life in childhood, we opted for the Child-Oral Impacts of Daily Performance (Child-OIDP)[5] which was developed from an abstract model of the oral quality of life, and submitted for psychometric evaluation[6]

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