ASSESSMENT OF DRUG UTILIZATION PATTERN OF STATIN THERAPY FOR PRIMARY PREVENTION OF CARDIOVASCULAR RISK IN DIABETIC PATIENTS ATTENDING TERTIARY CARE TEACHING HOSPITAL OF CENTRAL INDIA

Abstract

Background: Diabetes Mellitus is one of the prevalent metabolic disease which is associate with dyslipidemia. This poses this patient for signicantly increased cardiovascular risk events like stroke, myocardial infarction etc. Statins are widely used among these patients for primary prevention of cardiovascular risk. This study emphasizes on pattern of statin therapy being practiced in Indian setup and lacunae related to with aspect of improving public health Methods: This study was a crossectional observational study conducted in a tertiary care teaching hospital of central India. The study was started after obtaining clearance from Institute Ethics Committee. The patients satisfying the inclusion criteria were recruited in this study after obtaining Informed consent. The diabetic patients were assessed for statin therapy and intensity of statin therapy widely prescribed and practiced with respect to Indian population. Results: Of total 2680 diabetic patients recruited in this study, 1800 (67.16%) were prescribed with statin therapy, of which 41.5% were males and 25.66% were females. 1280 diabetic patients were prescribed with Atorvastatin and 520 were prescribed with Rosuvastatin.Of all the available statins, Two statins, Atorvastatin and Rosuvastatin, was prescribed to the diabetic patients the most. Conclusion: This study will be providing baseline data regarding drug utilization pattern of statins in diabetic patients. This study will help in assessing the statin eligibility and to determine data pertaining to overuse or underuse of statins in diabetic patients. It also emphasizes the pattern of statin being prescribed based on its intensity. The data of this study will be useful to plan further research related cardiovascular risk and statin considering various factors for Indian population