How to identify HIV-infected individuals at risk for atherosclerotic events?

Abstract

There is concern about coronary heart disease (CHD) in the HIV-infected population using antiretrovirals. Across Europe and North America, this population is at a higher risk of myocardial infarction (MI) than the general population [1–3], although the difference seems to diminish in recent years [4]. Consequently, identifying HIV-infected individuals at risk for CHD, and more broadly for all atherosclerotic cardiovascular disease (ASCVD) events including CHD and stroke, is desirable albeit extremely challenging.