Assessment of Drug Related Problems in Patients with Cardiovascular Diseases in Tertiary Care Hospital: A Clinical Pharmacist Intervention

M Reshma,J Thipperudra,B Shailaja ,P Tasleem ,P Gouthami

doi:10.13189/ijccd.2020.070101

Abstract

Drug related problems in cardio vascular disease patients may lead to morbidity, mortality and the decreased quality of life. The main aim of the study is to assess, identify and resolve drug related problems in patients with Cardiovascular Diseases. A total of 150 cardiac patients were enrolled into the study. In our study, out of 150 we got 71 DRPs like Drug-Drug interactions 33(46.4%), ADRs 14(20%), indication without Drug 6(8.4%), drug use without indication 8(11.2%), sub therapeutic dose 10(14%). The association between risk factors like alcohol abuse, smoking, diabetes, hypertension increased risk of CVD. The P value was statistically significant in males than in females. In this study, for individuals with drug related problems of cardiovascular diseases, males were found to be more when compared with females due to risk factors such as smoking, alcoholism, life style etc. the drug related problems were high in patients aged between 40-60 years because of their multiple co-morbid conditions. Polypharmacy was the main predisposing factor for drug related problems.

Highlights

Cardiovascular disease is a major public health problem and one of the leading causes of premature death throughout the world
Cardiovascular disease is a global health problem reaching epidemic proportional in both developed and developing countries and it is the principal cause of morbidity and mortality universal (Karim MA et al 2015)
The objective of this study is to identify the type of drug related problems and assess the outcomes of drug related problems among cardiovascular disease patients

Summary

Introduction

Cardiovascular disease is a major public health problem and one of the leading causes of premature death throughout the world. According to world health organization report 2011, approximately 17.1 million people die due to cardiovascular disease each year, representing 30% of all deaths. Of these deaths, approximately 7.3 million people die of coronary heart disease and 6.2 million people die mainly from heart diseases and stroke, which are projected to remain the single leading cause of death. Drug related problems are a major safety issue for hospitalized patients and it may lead to reduced quality of life, increased hospital stay, and increases risk of morbidity and mortality. Lack of follow-ups and reassessment of therapeutic outcomes may contribute to drug related problems. (Adusumilli PK, Adepu R 2014)

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