Abstract
Background- Fine Needle Aspiration cytology (FNAC) is easy to do for diagnosis of lymphadenopathy, but it does not yield sufcient information for precise diagnosis. Cell block (CB) preparation in a way mimics the histopathological sections, thus help in sub classifying various lesions. Methods- This was observational study with evaluation of diagnostic efcacy in lymphadenopathy by ne needle aspiration cytology and cell blocks versus histopathology at a tertiary care hospital from June 2018 to Jan 2020. Results- In this study, (Combined FNAC plus Cell Block) showed concordance with histopathogical diagnosis in 90% cases. For Combined FNAC and Cell Block Sensitivity was 95%, Specicity was 100%, Diagnostic Accuracy was 95%.Conclusion- FNAC as the rst line approach supplemented by Cell Block in selected cases, where the information given by FNAC is in doubt or insufcient to guide clinical management. This strategy is likely to reduce the risk of misdiagnosis and the impact of cytological pitfalls
Published Version
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