Abstract

Introduction Vaccination is an effective method to prevent a number of infectious diseases. Vaccines have largely reduced morbidity, mortality and health care costs and have enhanced the quality of life of patients worldwide. Unfortunately, there’s adverse effect associated with vaccine, Most of the adverse events (AE) are fever and local pain, inflammations, vomiting, nausea. To reduce pain and fever associated with vaccination utilized paracetamol as prophylactically and also for treatment.

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