Abstract
Withania somnifera L (or Ashwagandha or Indian ginseng) is a sub-tropical medicinal plant of Solanaceae family that is used by folk healers for multipurpose ailments in alternative system of treatment. It serves as bioactive ingredient in more than 100 ayurvedic formulations of Ayurveda, Siddha, and Unani medication. The ethnopharmacological application of Ashwagandha includes adaptogenic, anti-convulsion, anti-microbial anti-sedative, anti-stress, arthritis, geriatric debilities, mental disorders, and neurological disorders. The present study included validation of antimicrobial properties of commercially available W. Somnifera powder against human pathogens viz., P. aeruginosa (gram -ve), S. aureus (gram +ve), and E. coli (gram -ve). The experimental results exhibited that chloroform, isopropanol, and distilled water extract of W. somnifera showed significant antibacterial action, 15.5 mm, 20.5 mm, and 27 mm clear zones (in radius) against P. aeruginosa, S. aureus, and E. coli respectively. The prospects of Ashwagandha powder could be its applicability as a folklore pharmacological agent and by means of a harmless routine dietary supplement to boost immunity and prevent bacterial infection.
Published Version
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