Application of CT guidedpercutaneous lung biopsy in diagnosis of AIDS-related pulmonary disease

Abstract

：Objective To discuss theaccuracy and safety of CT guided percutaneous lung biopsy in the diagnosis of AIDS-relatedpulmonary disease. Methods The clinical and the pathological results of CT guidedpercutaneous lung biopsy of 6 cases -with AIDS-related lung disease were analyzed. Results6 patients had various degrees of chest tightness, white foam sputum occurred in 4 casesand high fever in 3 cases (＞ 39.5 ℃) before lung biopsy. The WBCwere increased in 2 cases, decreased in 4 cases; ESR were increased in 3 patients, CEA wasincreased to 52.20 ng/mL in 1 cases. The chest CT showed lung flake or crumb lesions inall the patients. The pathology for biopsy revealed that 5 cases developed inflammatorychange (including granuloma change in 2 cases) and 1 case with lung cancer. Penicilliummarneffe was detected in 2 cases and rhodococcus equi in one case. Tuberculosis occurredin 2 cases and pulmonary adenoid cystic carcinoma in 1 case. Only 1 patient developed alittle pneumothorax postoperation. All the patients were treated according to thepathological results of lung biopsy and received good treatment expect 1 patient with lungcancer. Conclusions CT can clearly show the viscera internal lesions and the relationbetween the lesions and the surrounding tissue structure, so CT guided percutaneous lungbiopsy is a safe and effective method for obtaining pathological data of pulmonarydisease, it can provide important basis for the etiological diagnosis and help to raisethe survival rate of the patients. Key words: Acquired immunodeficiency syndrome; Biopsy; Tomography,helical CT