Abstract
Antioxidant properties of Mentha pulegium and histopathological evaluation of its ameliorating effect on experimental acute hepatic injury
Highlights
Liver disease is typically linked to alcohol or drugs, but there are over 100 known forms of liver diseases all over the world caused by a variety of causes affecting human being from infants to older adults
There are no detailed reports on hepatoprotective effects of M. pulegium growing in Saudi Arabia
The antioxidant properties of plant extracts depends on its capability to act as radical scavenger, hydrogen donor or reducing agent according to their total phenol and flavonoid contents [19]
Summary
Liver disease is typically linked to alcohol or drugs, but there are over 100 known forms of liver diseases all over the world caused by a variety of causes affecting human being from infants to older adults. In Kingdom of Saudi Arabia, hepatic disorders constitute an important common health problem usually associated with significant mortality and morbidity rates [1,2]. These disorders include mostly hepatitis B and C, in addition to other causes such as autoimmune hepatitis, Wilson’s disease and non-alcoholic steatohepatitis [3]. Treatment of liver failure remains one of the main critical problems in clinical medicine and current drug therapy for management of liver diseases causes adverse side effects [4]. M. pulegium is the most common species of Mentha in Saudi Arabia, known as AlMedina mint and usually added in commercial spice mixtures and herbal tea [7]. There are no detailed reports on hepatoprotective effects of M. pulegium growing in Saudi Arabia
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