Abstract

An analytical study of histological hazards estimation and comparison between cholecystitis and cholelithiasis by routine, mucin and lipid histochemistry procedures

Highlights

  • Gallbladder carcinoma is found in up to 1.5% of cholecystectomy specimens of gall bladder diseases like cholecystitis and cholelithiasis

  • The result of lipid histochemistry with Sudan Black B stain overall and concern with all histological layers from inside out, indicated accumulation of phospholipids and scattered lipids predominantly in supranuclear region of epithelial cells and rest of the layer and average calculated in cholelithiasis 99.09%, in cholecystitis 76.76% and in control 38.75% (Figure 1)

  • In the current case control study an attempt is made to estimate and compare the overall histological alterations in cholelithiasis, cholecystitis and control human gall bladders by the evaluation of overall and average percentages of all histological hazards and other findings concerned with all histological layers by the application of routine histochemistry, mucin histochemistry and lipid histochemistry

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Summary

Introduction

Gallbladder carcinoma is found in up to 1.5% of cholecystectomy specimens of gall bladder diseases like cholecystitis and cholelithiasis. Cholecystectomy specimen’s losses evidence of rare pathologies when send for histopathological reports such as premalignant benign lesions, carcinoma in medulla and early carcinomatous stage. To avoid such major mistakes every cholecystectomy specimen should be routinely examined histologically. Multiparous females between 45 to 55 age ranges are predominant sufferer of cholecystitis and cholelithiasis, which is most common diseases, occurs in primate vertebrate & human gall bladder. These diseases victimizes alcoholic males and kids [1]. Percentages of bile calculus rose with age. 35% of adults over 45 years of age and 55% of those above age of

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