Antimicrobial activity of garlic and Pomegranate Peel extracts against some pathogenic bacteria

Abstract

The extracts of garlic and pomegranate peel were used against Pseudomonas aeruginosa, Proteus mirabilis, Staphylococcus aureus, E. coli, Klebsiella pneumoniae, Acinetobacter baumannii. The aqueous extracts of garlic and pomegranate peel were prepared and tested in vitro for evaluation antibacterial activity by agar well diffusion method. The antibiotics (imipenem, augmentin, ceftriaxone, levofloxacin, amikacin, gentamycin, trimethoprim–sulfamethoxazole, clindamycin, piperacillin) susceptibility were examined against tested bacteria by Kirby-Bauer disc diffusion method.The results revealed the inhibitory effect of extracts of garlic and pomegranate peel against the isolated bacteria. The inhibition zones caused by the garlic extracts were much higher than pomegranate peel that indicated the potency of the active components in garlic. The antibiotics activity test exhibited these bacteria were susceptible to antibiotics imipenem and resistant to augmentin and ceftriaxone. Whereas, the Klebsiella pneumoniae was more resistant to antibiotics than other tested bacteria. The present study indicated that the plant extract has very important role for prevention pathogenic bacteria and can be used for control causative agent.