Antimicrobial Activity of Compound Traditional Chinese Medicine Feizhu Powder

Abstract

Feizhu powder, which is a classical Chinese medicine prescription collected in the Chinese Veterinary Pharmacopoeia, comprises four kinds of Chinese herbs: Rhizoma dryopteridis crassirhizomatis, Radix polygoni multiflori (prepared), Fructus hordei germinatus and Soybean (fry). According to dose proportion in the prescription and preparation method collected in the Chinese Veterinary Pharmacopoeia, we have prepared the Feizhu powder. In order to research the antibacterial activity in vitro of homemade Feizhu powder, it was extracted with 95% ethanol and water, respectively. Then minimum inhibitory concentration (MIC) of the extract was detected against Streptococcus suis, Staphylococcus aureus and Escherichia coli by micro porous-plate method. The results showed that MICs of Feizhu powder water extract ranged from 250 mg/mL to 500 mg/mL. While MICs of Feizhu powder alcohol extract ranged from 31.25 mg/mL to 62.5 mg/mL. The test data indicated that antimicrobial activity of Feizhu powder alcohol extract is superior to that of water extract, this lay the foundation for the extract of the antibacterial active ingredients and further research on Feizhu powder.