Abstract
Malaria is a high health concern in endemic regions. Effective anti-malarial agents against Plasmodium falciparum infection are often studied for novel effective treatment. This study aimed to examine the anti-malarial properties of Pithecellobium jiringa (Dogfruit) skin extracts. Ethanol and ethyl acetate extracts of P. jiringa skin were assessed in vitro on the growth of P. falciparum. The IC50 values were 16.59 µg/mL and 4.897 µg/mL for the ethyl acetate and ethanol extracts, respectively. The results indicated that the P. jiringa skin ethanol extract demonstrated the highest potent inhibitory effect which is a promising agent against malaria. More studies are recommended to identify and characterize the active compounds in P. jiringa skin extract.
Published Version
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