Abstract
Anticoagulation properties of biomaterials are crucial for biomedical applications,especially for blood-contacting materials.Carboxylated graphene oxide complexes with L-glutamic acid was prepared.The complexes were characterized by FTIR,static contact angle(SCA),XRD and TG.The anticoagulation properties of complexes were evaluated by hemolysis test and recalcification time test.The results show that the L-glutamic acid has been coordinated on graphene oxide sheet layer.The plasma recalcification time were prolonged greatly as compared to whole blood.At lower concentrations,the hemolysis rates was less than 5%,which met the requirements of biomedical materials.
Published Version
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