Abstract

Biofilm is a collection of microbial cells irreversibly attached to a surface and encased in an Extracellular Polymeric Substance (EPS) matrix produced by itself and shows phenotypic changes such as changes in growth rates and changes in gene transcription from planktonic cells or their free cells. Bacteria that often cause biofilms are Staphylococcus aureus, which is widely distributed in nature. Some live like normal flora in humans in the axilla, inguinal and perineal region, and anterior nostrils. Approximately 25-30% of humans carry Staphylococcus aureus in the nasal cavity and skin. This review aims to determine the antibacterial and antibiofilm activity of plants containing volatile oil compounds against Staphylococcus aureus. The method used in this review is a narrative review approach. This method is a secondary research method that does not have specific guidelines in its preparation (non-systematic review) by collecting data or sources related to a particular topic obtained from various sources such as journals, the internet, and other libraries. From hundreds of journals, 20 journals have the activity of inhibiting Staphylococcus aureus, the conclusion obtained after reviewing hundreds of literature that essential oils have inhibitory activity and even destroy biofilms.

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