Abstract

Different doses of ethanolic extract of Stephania glabra tuber were evaluated for antihyperglycemic activity in alloxan induced diabetic mice. The oral administration of 100, 200 and 500 mg/kg body weight showed significant hypoglycemic activity. Glibenclamide (oral hypoglycemic agent, 25 mg/kg, p.o.) has been used as standard. Key words: Stephania glabra, Menispermaceae, hydroxypalmatine, alloxan, glibenclamide, hypoglycemic activity DOI:10.3329/jom.v11i1.4262 J Medicine 2010: 11: 17-19

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