Abstract
The steric effect of o-methyl groups is much more pronounced for N-alkylation with Mel, Etl, and PriI or aza-aromatic compounds than for S-alkylation of heterocyclic thiones. This is explained by comparison of van der Waals interactions in the transition states of chosen homomorphic systems; an angular transition state is shown to conform with the measured kinetic constants.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Journal of the Chemical Society, Perkin Transactions 2
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
