Abstract

Objective To observe the treatment efficacy of blepharospasm in children. Methods The data of 240 eyes of 120 cases with blepharospasm from May 2016 to Apr.2017 were collected. The optical history, symptom, visual acuity, refraction, Schirmer Ⅰtest(SIT), fluorescent staining(FL) and break-up time(BUT) were observed.All cases received application of recombinant bovine basic fibroblast growth factor(r-bFGF) eye-gel combined with warm compress to the lid.Compound tropicamide eye drops was applied to children with myopia.The followed up time was half a year. Results According to the degree of blepharospasm, 13 cases were grade Ⅰ, grade Ⅱ in 88 cases, and grade Ⅲ in 19 cases. There were 60 cases with myopia, 6 cases with astigmatism, and 3 cases with amblyopia. SIT were≤10 mm in 77 cases, BUT were<10 s in 73 cases, and FL were positive in 23 cases.After treatment, 91 cases had complete remission, 29 cases had partial remission, and the efficiency rate was 100%. Conclusion Dioptroscopy should be performed on children with blepharospasm, and half of the children with ametropia. Application of r-bFGF eye-gel combined with warm compress to the lid for the treatment of children with blepharospasm are effective. Key words: Blepharospasm, children; r-bFGF eye-gel; Ametropia; Treatment

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