Analysis of the effect of preoperative nutritional risk screening on clinical outcomes, immune function and nutritional index in patients with colorectal cancer

Abstract

Objective To analyze the effect of preoperative nutritional risk screening on clinical outcomes, immune function and nutritional index in patients with colorectal cancer. Methods 140 cases with colorectal cancer between September 2015 and March 2016 were selected, according to the score of NSR 2002 screening scale, they were divided into A group (87 cases), which was less than 3 points, and B group (53 cases), which was more than 3 points.A group was divided into non nutrition support group (50 cases) and nutrition support group (37 cases), while B group was divided into non nutrition support group (21 cases) and nutrition support group (32 cases). The clinical outcomes, immune function, nutritional index and complication were compared. Results The clinical outcomes[(1.9±0.5)d vs.(1.3±0.4)d], immune function[(31.93±5.27)pg/mL vs.(31.46±4.68)pg/mL], nutritional index[(2.09±0.36)g/L vs.(2.01±0.32)g/L]of the non nutrition support group and nutrition support group of A group had no significant differences (t=0.992, 0.981, 0.991, all P>0.05). The clinical outcomes[(3.5±0.7)d vs.(2.2±0.6)d], immune function[(25.49±5.49)pg/mL vs.(56.41±9.52)pg/mL], nutritional index[(1.71±0.40)g/L vs.(1.94±0.35)g/L]of one week after operation of the non nutrition support group in B group were worse than nutrition support group (t=4.033, 7.335, 4.997, all P 0.05). The complication rate of non nutrition support group of A group was 21.7%, which was higher than that in nutrition support group (9.3%)(χ2=7.299, P<0.05). Conclusion For newly admitted patients with colorectal cancer, nutritional risk screening in early admission, according to the physiological index test results such as nutritional index and screening results, get the nutritional status of patients, choose reasonable nutrition drug dosage and the infusion way on the need of nutritional support of patients in a timely and reasonable nutrition support, improve the postoperative nutritional status, and accelerate the postoperative recovery. Key words: Nutritional risk screening; Colorectal neoplasms; Immune function; Nutritional index