ANALYSIS OF STRUCTURE AND ANTIMICROBIAL ACTIVITY OF CeO2 AND Nd2O3 NANOPARTICLES

Eryanti Kalembang,Yelvia Deni,Putri Widya Pangestika,Defi Rahma Santi,Bambang Sugeng,Hanif Yuliani,Moch. Setyadji,Suyanti Suyanti,Setyo Purwanto,Rina Dewi Mayasari

doi:10.21009/spektra.043.01

Abstract

Cerium oxide (CeO2) and Neodymium oxide (Nd2O3) nanoparticles using local content have been synthesized by precipitation method. The CeO2 and Nd2O3 nanoparticles were characterized by X-Ray Diffraction (XRD) and Fourier Transform Infrared (FTIR) to analyze the material phase and structure. The XRD spectrum shows that CeO2 and Nd2O3 nanoparticles have face-centered cubic and hexagonal, and cubic, respectively. The anti-microbial activity of CeO2 and Nd2O3 nanoparticles was analyzed by diffusion method using gram-negative bacteria (E. coli, S. aureus, P. aeruginosa), and gram-positive bacteria (S. entericatyphi, L. monocyogenes), and fungus (C. albicans). The result confirms that CeO2 and Nd2O3 nanoparticles have the capability of microbial pathogen inhibition. The CeO2 nanoparticles have the effective activities of inhibition for the microbial of S. aureus and S. entericatyphi, whereas Nd2O3 nanoparticles can inhibit the microbial of P. aeruginosa, S. entericatyphi, and L. monocyogenes.

Highlights

Nowadays, nanotechnology, primarily nanomaterials research and development, has been widely used for various applications in daily life, such as medicine and food [1], sensors [2], energy [3], and others
The results showed that G-CeO2 nanoparticles had higher activity than C-CeO2 against Escherichia coli, Pseudomonas aeruginosa, Streptococcus pneumonia, and Proteus Vulgaris bacteria [7]
We reported the materials properties and anti-microbial activities of CeO2 and Nd2O3 nanoparticles

Summary

INTRODUCTION

Nanotechnology, primarily nanomaterials research and development, has been widely used for various applications in daily life, such as medicine and food [1], sensors [2], energy [3], and others. The CeO2 and Nd2O3 have great potential to produce new various antibiotics [6,7,8]. Several previous studies have reported anti-microbial activity on REE nanomaterials [6,7,9]. The results showed that G-CeO2 nanoparticles had higher activity than C-CeO2 against Escherichia coli, Pseudomonas aeruginosa, Streptococcus pneumonia, and Proteus Vulgaris bacteria [7]. We reported the materials properties and anti-microbial activities of CeO2 and Nd2O3 nanoparticles. Anti-microbial activities of the nanoparticles were tested with six types of microbes, i.e., Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Salmonella entericatyphi, Listeria monocytogenes, and Candida albicans. The results of this research are the preliminary study of REE research for antibiotic applications which are expected to be new potential antibiotics

METHOD

AND DISCUSSION

CONCLUSION