Abstract

目的 探讨吸烟与2型糖尿病病足早期危险性的关系.方法 将104例2型糖尿病患者(T2DM)根据有否吸烟分为吸烟组(45例)和非吸烟组(59例),检测空腹血糖(FBG)、餐后2 h血糖(PBG2h)、糖化血红蛋白(HbA1c)、血胆固醇(TC)、甘油三脂(TG)、高密度和低密度脂蛋白胆固醇(HDL-C、LDL-C)、肾功能(BUN、Cr)、C反应蛋白(CRP)、踝动脉-肱动脉血压比值(ABI)等指标,进行组间对比分析.结果 吸烟组与非吸烟组比较,CRP增高[(8.45±13.15)vs(3.56±4.58),P<0.01],HDL-C降低[(1.04±0.26)vs(1.22±0.45),P<0.05];吸烟组糖尿病病足早期发生率显著高于非吸烟组(P<0.05).结论 吸烟是糖尿病病足早期重要的独立危险因素。

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