Analysis of pregnancy outcome in patients with cervical cancer after cervical cold knife conization

Abstract

Objective To explore the effect of pregnancy outcome with cervical cold knife conization in pa -tients with early stage cervical cancer .Methods 23 patients with cold knife conization and 21 patients with radical trachelectomy were collected .The pregnancy outcome and perinatal infants between the two groups were compared . Results The pregnancy rate was 82.6%in the observation group,71.4%in the control group,there was statistically significant difference（χ2 =8.654,P=0.002）;the section rate was 37.5% in the observation group,30.8% in the control group,there was statistically significant difference （χ2 =9.645, P =0.000 ）;10 cases of term delivery （62.5%）and birth weight was（3.27 ±1.15）in the observation group,term delivery（69.2%）and birth weight was （2.81 ±0.96）in the control group,proportion and birth weight were statistically significant differences （χ2 =11.671, P=0.000）（t =9.683,P=0.000）;there were statistical significance in the outcome of pregnancy （Fisher P=0.036）and perinatal infants（Fisher P=0.034）among patients with different cervical conization height;the relapse rate was 4.4% in observation group,9.5% in the control group,the relapse rate of the two groups had significant difference（Fisher P =0.039）.Conclusion Compared with radical trachelectomy ,patients treated by cold knife conization has high pregnancy rate and high cesarean section rate ,which can influence the outcome of pregnancy and perinatal infants . Key words: Uterine Cervical Neoplasms; Postoperative Period; Gravidity