Abstract

The article presents the results of a retrospective epidemiological analysis of the incidence of typhoid fever in the Kyrgyz Republic and the results of a survey aimed at studying the immune status of the population. It was found that despite the emerging trend of reducing the incidence of typhoid fever, this problem in Kyrgyzstan remains extremely relevant due to high rates that significantly exceed those of developed countries. The leading route of transmission of typhoid fever in the Kyrgyz Republic is water, and the territories at risk are the southern regions of the Republic. A permanent epidemic focus of typhoid fever has been identified in the Jalal-Abad region, where radiation remains an additional factor of negative impact on the population of Mailuu-Suu over the past thirty years against the background of low availability of high-quality drinking water. The effect of the radiation factor is associated with the development of immunological insufficiency, which creates the basis for the formation of risk groups for infectious diseases, including typhoid fever.

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