Abstract
Cytodiagnosis of pleural effusions is very important in the clinical assessment of respiratory diseases. The existence of cancerous cells in effusions is a good evidence of indicating malignant nature of the disease process, and thus determines the treatment and prognosis of the patients. Observation of the cells derived from pleural effusion with light microscopy or transmission electron microscopy can perform detailed analysis of the cytoplasm and the nucleus. It is expected that other useful morphologic data is still contained on the plasmic membrane or cell surface. However, this can only be explored by scanning electron microscopy. In order to understand more comprehensively the surface structure of malignant cells in pleural effusion, specimens obtained from 69 patients including 26 men and 43 women were examined with scanning electron microscope in this study. The clinical diagnosis was primary adenocarcinoma of the lung in 46 patients, breast cancer in 20 patients and ovarian cancer in 3 patients. Pleural metastasis occurred in all of the patients and their chest X-ray films showed pleural effusion.
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Schedule a callMore From: Proceedings, annual meeting, Electron Microscopy Society of America
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