An Observational Study to To Find Impact of Covid 19 Infection on Causation and Prognosis of Pancreatitis in a Tertiary Care Center

Abstract

Objective :To find impact of covid 19 infection on causation and prognosis of pancreatitis Design :Prospective observational study Setting :A large, academic, tertiary medical center Methodology:Clinical and laboratory data of all consecutive patients with a primary diagnosis of AP during past 6months with history of covid 19 infection was collected .Clinical and radiological grading was taken into consideration for finding severity. Results:out of 30 patient 4 patients had severe covid 19 infection requiring more than 10days of hostilization but though 1 of those 4patient developed recurrent pancreatitis but severity score was less(clinical and radiological).14 had mild covid 19 infection with minimal respiratory and more of GI symptoms .Out of these 14 ,10 developed severe acute necrotizing pancreatitis requiring ICU stay and prolonged hospital stay .12 patients had mild covid 19 infection with respiratory symptoms .10 of them had pancreatitis of mild severity ,2 developed severe necrotizing pancreatitis. Interpretation and conclusion:Based on our study we conclude that more than severe covid 19infection mild covid 19infection with GI symptoms has a greater impact on the prognosis of patient with pancreatitis.However there is still insufficient evidence showing that covid 19 can cause AP or negatively impact prognosis.Additional major studies are needed to clarify relationship between these two entities