An inquiry into the relationship among pathology, clinic and laboratory indexes of the severe viral hepatitis

Abstract

This study was to analyze the relationship among pathology, clinic and laboratory indexes in 62 cases of the acute severe hepatitis (ASH) and 72 cases of the subacute severe hepatitis(SSH) to offer a correct diagnosis and recognition of the disease. A total of 134 severe hepatitis cases with confirmed pathology treated in a course of 24 years were analyzed by programs of EXCEL 2000. When compared ASH with SSH, the onset of the age were 40 +/- 13 years old and 44 +/- 15 years old, P < 0.05, the rates of hepatitis coma were 100% and 66.7% respectively. The liver weight of all the cases decreased. The tests of TBiL, PTA, Cho, NH3 and WBC between ASH and SSH had significant differences. Hepatic encephalopathy is a necessary criterion for ASH. The TBiL, PTA and Cho changes are closely related with severe viral hepatitis, they not only are the essential laboratory indexes but also the indispensable factors for disease development and prognosis of severe viral hepatitis.