An Assessment of Renal Function with Pulsatile Perfusion During Proximal Graft Using Cardiac Contraction in Coronary Artery Bypass Graft Surgery

Abstract

Background: Short-term pulsatile perfusion during cardio pulmonary bypass has shown higher protection for renal physiology, following standard preservation of glomerular filtration and reduction of renal tissue damage. Methods: In this randomized clinical trial study, 70 patients, who had undergone CABG surgery were divided to 2 groups; pulsatile and non-pulsatile groups. The researchers transferred continuous blood flow to pulsatile blood flow during proximal graft using cardiac contraction. Patients’ laboratory tests, such as blood urea nitrogen (BUN) and creatinine were checked preoperatively, at the arrival of the open heart intensive care unit (ICU-OH), and 24 and 48 hours after admission. Results: Both case and control groups had significantly increased BUN and creatinine. Increased creatinine on the first and second postoperative day was significantly higher in the control group. Furthermore, BUN increased on the second day in the control group and was significantly higher than the case group Conclusions: Despite the rise in BUN and creatinine in the 2 groups, there were no cases of renal failure in the patients. However, the results of this study regarding creatinine and BUN criteria were supported by the pulsatile perfusion method during the proximal graft by using a cardiac contraction in CABG surgery.